Evidence map›Paper›PMID 37262390›Full record

ArticleJCO precision oncology2023

Response to Repotrectinib After Development of

Monica F Chen, Soo-Ryum Yang, Jinru Shia, Jeffrey Girshman, Sippy Punn, Clare Wilhelm, Mark G Kris, Emiliano Cocco, Alexander Drilon, Nitya Raj

Abstract read
In one paragraph

Article in JCO precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Review
  6. Molecular Basis of Breast Tumor Heterogeneity.Advances in experimental medicine and biology · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Monica F ChenThoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY.ORCID 0000-0002-7485-2463
Soo-Ryum YangDepartment of Pathology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.
Jinru ShiaDepartment of Pathology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.ORCID 0000-0002-4351-2511
Jeffrey GirshmanDepartment of Radiology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.ORCID 0000-0003-0533-0423
Sippy PunnGastrointestinal Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.
Clare WilhelmThoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY.ORCID 0000-0003-2437-5387
Mark G KrisThoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY.
Emiliano CoccoDepartment of Biochemistry and Molecular Biology/Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL.ORCID 0000-0002-1397-2656
Alexander DrilonThoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY.ORCID 0000-0001-6806-9061
Nitya RajGastrointestinal Medical Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.ORCID 0000-0002-1385-9995

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Investigational Cancer Therapeutics Training Program (ICTTP)T32CA009207 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Omar Abdel-Wahab, Alexander Drilon · 1985 to 2026
$13.7M
Understanding tumor addiction to TRK fusions and sensitivity to TRK inhibitionR01CA226864 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DRILON, ALEXANDER, VENTURA, ANDREA · 2018 to 2021
$2.5M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA226864NCI NIH HHS T32 CA009207
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PyrazolesReceptor, trkAHumansMacrocyclic CompoundsMutationProtein Kinase InhibitorsMacrocyclic CompoundsProtein Kinase InhibitorsPyrazolesReceptor, trkArepotrectinib

Identifiers

PMID37262390
PMCPMC10309517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.