Evidence map›Paper›PMID 37262296›Full record

ArticleFamily practice2024

General Practitioners perspectives on infant telomere length screening after a pregnancy complication: a qualitative analysis.

Carolyn J Puglisi, Joshua McDonough, Tina Bianco-Miotto, Jessica A Grieger

Open access · hybridAbstract read
In one paragraph

Article in Family practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carolyn J PuglisiSchool of Agriculture, Food and Wine, University of Adelaide, Adelaide 5005, Australia.
Joshua McDonoughSchool of Public Health, University of Adelaide, Adelaide 5005, Australia.
Tina Bianco-MiottoSchool of Agriculture, Food and Wine, University of Adelaide, Adelaide 5005, Australia.ORCID 0000-0002-8431-5338
Jessica A GriegerRobinson Research Institute, University of Adelaide, Adelaide 5005, Australia.ORCID 0000-0003-1515-948X
The University of Adelaide · AU

Funding

National Health and Medical Research Council APP2000905
6 · The paper itself

Abstract

backgroundPregnancy complications can impact the mother and child's health in the short and longterm resulting in an increased risk of chronic disease later in life. Telomere length is a biomarker of future cardiometabolic diseases and may offer a novel way of identifying offspring most at risk for future chronic diseases. OBJECTIVE(S): To qualitatively explore General Practitioners' (GPs) perspectives on the feasibility and uptake for recommending a telomere screening test in children who were born after a pregnancy complication.

methodsTwelve semi-structured interviews were conducted with GPs within metropolitan Adelaide, South Australia. Interviews were audio recorded, transcribed verbatim, and analysed for codes and themes.

resultsTwo themes were generated: ethical considerations and practical considerations. Ethically, the GP participants discussed barriers including consenting on behalf of a child, parental guilt, and the impact of health insurance, whereas viewing it for health promotion was a facilitator. For practical considerations, barriers included the difficulty in identifying people eligible for screening, maintaining medical communication between service providers, and time and financial constraints, whereas linking screening for telomere length with existing screening would facilitate uptake.

conclusionsGPs were generally supportive of potential telomere screening in infants, particularly via a saliva test that could be embedded in current antenatal care. However, several challenges, such as lack of knowledge, ethical considerations, and time and financial constraints, need to be overcome before such a test could be implemented into practice.

Indexed as

General PractitionersPregnancy ComplicationsQualitative ResearchAdultAttitude of Health PersonnelFemaleHumansInfantInterviews as TopicMaleMass ScreeningPregnancySouth AustraliaTelomereAustraliaGPsinfant screeningpregnancy complicationtelomere length

Identifiers

PMID37262296
PMCPMC11636557
OpenAlexW4379058288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.