ArticleScience (New York, N.Y.)2023
A global catalog of whole-genome diversity from 233 primate species.
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Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.
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131citing papers in PubMed
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Who cites it
131 citing papers in PubMed.
- A curated genome-scale nucleotide diversity panel of non-human primates.Genome biology · 2026Article
- Agriculture affects genetic diversity and functional connectivity in an ecologically flexible West African primate.Heredity · 2026Article
- The gene-regulatory evolution of the human skeleton.Nature · 2026Article
- Parting ways: Pan-Homo divergence revisited.Primates; journal of primatology · 2026Review
- Gene regulatory innovations from transposable elements in primate cerebellum development.Nature communications · 2026Article
- The howler monkey genome provides new insights into the distinctive howling and folivorous adaptations of New World monkeys.Genome biology · 2026Article
- Positive selection on brain cis-regulatory elements in the human lineage drives changes in gene expression and susceptibility to neuropsychiatric disorders.HGG advances · 2026Article
- A Systematic Revision of the Late Miocene Cercopithecid Monkeys From the Lemudong'o Formation, Kenya.American journal of biological anthropology · 2026Article
- Evolutionary History and Functional Divergence of Hydroxycarboxylic Acid Receptors in Primates.Genome biology and evolution · 2026Article
- Multi-Locus Nuclear Marker Assessment of Genetic Diversity in Swiss Orthoptera Unveils Conservation Status Limitations.Molecular ecology · 2026Article
- Challenges in predicting chromatin accessibility differences between species.NAR genomics and bioinformatics · 2026Article
- Census and genetic analysis of the United States marmoset population.bioRxiv : the preprint server for biology · 2026Article
- Conserved structural features of the lncRNA HOTAIR in breast cancer cells.bioRxiv : the preprint server for biology · 2026Article
- Rapid centromere turnover and the adaptive radiation of lemurs.bioRxiv : the preprint server for biology · 2026Article
- Sequence alignment of the primate lineage reveals evolutionary divergence and conserved secondary structural motifs in noncoding RNAs.bioRxiv : the preprint server for biology · 2026Article
- Virtual reconstruction and analysis of the face of DFN3-150 Paradolichopithecus aff. arvernensis specimen from Dafnero, Greece.Scientific reports · 2026Article
- Genomic approaches for understanding the evolution of the human brain.Nature neuroscience · 2026Review
- Ubiquitous impact of natural selection on nucleotide diversity in 178 species of primates.Genome biology · 2026Article
- Ancient regulatory evolution shapes individual language abilities in present-day humans.Science advances · 2026Article
- CrossFilt: a cross-species filtering tool that eliminates alignment bias in comparative genomics studies of primates.Genome biology · 2026Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
75 authors.
Lukas F K KudernaIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0002-9992-9295
Hong GaoIllumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA 94404, USA.ORCID 0000-0001-6274-4513
Mareike C JaniakSchool of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK.ORCID 0000-0002-7759-2556
Martin KuhlwilmIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0002-0115-1797
Joseph D OrkinIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0001-6922-2072
Thomas BataillonBioinformatics Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-4730-2538
Shivakumara ManuAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.ORCID 0000-0002-9114-8793
Alejandro ValenzuelaIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0002-2252-3887
Juraj BergmanBioinformatics Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-9415-2747
Marjolaine RousselleBioinformatics Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-3930-0732
Felipe Ennes SilvaResearch Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development, Estrada da Bexiga 2584, CEP 69553-225, Tefé, Amazonas, Brazil.ORCID 0000-0002-1315-0847
Lidia AguedaCNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri I Reixac 4, 08028 Barcelona, Spain.ORCID 0000-0003-3358-2759
Julie BlancCNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri I Reixac 4, 08028 Barcelona, Spain.ORCID 0000-0002-5367-0628
Marta GutCNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri I Reixac 4, 08028 Barcelona, Spain.ORCID 0000-0002-4063-7159
Dorien de VriesSchool of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK.ORCID 0000-0002-6809-0052
Ian GoodheadSchool of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK.ORCID 0000-0002-3110-9442
R Alan HarrisHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-7333-4752
Muthuswamy RaveendranHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-6185-4059
Axel JensenDepartment of Ecology and Genetics, Animal Ecology, Uppsala University, SE-75236 Uppsala, Sweden.ORCID 0000-0003-1766-560X
Idrissa S ChumaTanzania National Parks, Arusha, Tanzania.ORCID 0000-0001-6622-8321
Julie E HorvathNorth Carolina Museum of Natural Sciences, Raleigh, NC 27601, USA.ORCID 0000-0002-6426-035X
Christina HvilsomCopenhagen Zoo, 2000 Frederiksberg, Denmark.ORCID 0000-0001-7870-6888
David JuanIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0003-1912-9667
Peter FrandsenCopenhagen Zoo, 2000 Frederiksberg, Denmark.ORCID 0000-0001-7131-0944
Joshua G SchraiberIllumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA 94404, USA.
Fabiano R de MeloUniversidade Federal de Viçosa, Viçosa, Brazil.ORCID 0000-0001-9958-2036
Fabrício BertuolUniversidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas 69080-900, Brazil.ORCID 0000-0001-6431-6950
Hazel ByrneDepartment of Anthropology, University of Utah, Salt Lake City. UT 84102, USA.ORCID 0000-0002-0351-3181
Iracilda SampaioUniversidade Federal do Para, Bragança, Para, Brazil.
Izeni FariasUniversidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas 69080-900, Brazil.ORCID 0000-0002-1416-4351
João ValsecchiResearch Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development, Tefé, Amazonas, Brazil.ORCID 0000-0002-9138-0381
Malu MessiasUniversidade Federal de Rondônia, Porto Velho, Rondônia, Brazil.ORCID 0000-0002-8322-3327
Maria N F da SilvaInstituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brazil.ORCID 0000-0001-7613-8004
Mihir TrivediLaboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India.
Rogerio RossiInstituto de Biociências, Universidade Federal do Mato Grosso, Cuiabá, MT, Brazil.ORCID 0000-0003-2353-5000
Tomas HrbekUniversidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL), Manaus, Amazonas 69080-900, Brazil.ORCID 0000-0003-3239-7068
Nicole AndriaholinirinaLife Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar.
Clément J RabarivolaLife Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar.
Alphonse ZaramodyLife Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga, Mahajanga, Madagascar.
Clifford J JollyDepartment of Anthropology, New York University, New York, NY 10003, USA.
Jane Phillips-ConroyDepartment of Neuroscience, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-8987-3419
Gregory WilkersonKeeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop TX 78602, USA.ORCID 0000-0002-3773-1064
Christian AbeeKeeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop TX 78602, USA.
Joe H SimmonsKeeling Center for Comparative Medicine and Research, MD Anderson Cancer Center, Bastrop TX 78602, USA.ORCID 0000-0003-1815-6831
Eduardo Fernandez-DuqueDepartment of Anthropology, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-3993-7912
Sree KanthaswamySchool of Mathematical and Natural Sciences, Arizona State University, Phoenix, AZ 85004, USA.
Fekadu ShiferawGuinea Worm Eradication Program, The Carter Center Ethiopia, Addis Ababa, Ethiopia.
Dongdong WuState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.ORCID 0000-0001-7101-7297
Long ZhouCenter for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.ORCID 0000-0001-7596-2691
Yong ShaoState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.ORCID 0000-0003-1704-8425
Guojie ZhangCenter for Evolutionary and Organismal Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.ORCID 0000-0001-6860-1521
Julius D KeyyuTanzania Wildlife Research Institute (TAWIRI), Head Office, P.O. Box 661, Arusha, Tanzania.ORCID 0000-0002-6888-4987
Sascha KnaufInstitute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-5744-4946
Minh D LeDepartment of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University, Hanoi, Vietnam.ORCID 0000-0002-2953-2815
Esther LizanoIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0003-3304-9807
Stefan MerkerDepartment of Zoology, State Museum of Natural History Stuttgart, Stuttgart, Germany.ORCID 0000-0003-3142-7720
Arcadi NavarroIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0003-2162-8246
Tilo NadlerCuc Phuong Commune, Nho Quan District, Ninh Binh Province, Vietnam.
Chiea Chuen KhorGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
Jessica LeeMandai Nature, 80 Mandai Lake Road, Singapore.ORCID 0000-0003-0757-4237
Patrick TanGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore.ORCID 0000-0002-0179-8048
Weng Khong LimSingHealth Duke-NUS Institute of Precision Medicine (PRISM), Singapore.ORCID 0000-0003-4391-1130
Andrew C KitchenerDepartment of Natural Sciences, National Museums Scotland, Chambers Street, Edinburgh EH1 1JF, UK, and School of Geosciences, Drummond Street, Edinburgh EH8 9XP, UK.ORCID 0000-0003-2594-0827
Dietmar ZinnerCognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0003-3967-8014
Ivo GutCNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri I Reixac 4, 08028 Barcelona, Spain.ORCID 0000-0001-7219-632X
Amanda D MelinDepartment of Anthropology and Archaeology, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-0612-2514
Katerina GuschanskiDepartment of Ecology and Genetics, Animal Ecology, Uppsala University, SE-75236 Uppsala, Sweden.ORCID 0000-0002-8493-5457
Mikkel Heide SchierupBioinformatics Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-5028-1790
Robin M D BeckSchool of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK.ORCID 0000-0002-7050-7072
Govindhaswamy UmapathyAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.ORCID 0000-0003-4086-7445
Christian RoosGene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, Germany.ORCID 0000-0003-0190-4266
Jean P BoubliSchool of Science, Engineering & Environment, University of Salford, Salford M5 4WT, UK.ORCID 0000-0002-5833-9264
Jeffrey RogersHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-7374-6490
Kyle Kai-How FarhIllumina Artificial Intelligence Laboratory, Illumina Inc., Foster City, CA 94404, USA.ORCID 0000-0001-6947-8537
Tomas Marques BonetIBE, Institute of Evolutionary Biology (UPF-CSIC), Department of Medicine and Life Sciences, Universitat Pompeu Fabra. PRBB, C. Doctor Aiguader N88, 08003 Barcelona, Spain.ORCID 0000-0002-5597-3075
Funding
Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative SupplementP40OD024628 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WILLIAM D HOPKINS · 2017 to 2026
$15.7MSTATISTICAL DATA ENCLAVE COREP30AG012836 · NIA · UNIVERSITY OF PENNSYLVANIA · PI COE, NORMA B · 1999 to 2024
$14.0MPopulation Science Research Center Development CoreR24HD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI SMITH, HERBERT L. · 2003 to 2017
$9.8MNIA NIH HHS P30 AG012836NICHD NIH HHS R24 HD044964NIH HHS P40 OD024628
Abstract
The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families and geographic regions to be associated with climate and sociality, but not with extinction risk. Furthermore, mutation rates differ across species, potentially influenced by effective population sizes. Lastly, we identified extensive recurrence of missense mutations previously thought to be human specific. This study will open a wide range of research avenues for future primate genomic research.
Indexed as
Biological EvolutionGenetic VariationPrimatesAnimalsGenomeHumansMutation RatePhylogenyPopulation Density
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