Evidence map›Paper›PMID 37262087›Full record

ReviewAmerican journal of physiology. Renal physiology2023

Less sodium, more potassium, or both: population-wide strategies to prevent hypertension.

Voravech Nissaisorakarn, George Ormseth, William Earle, Martha Catalina Morales-Alvarez, Swapnil Hiremath, Stephen P Juraschek

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Serum potassium and sodium levels and nutrient intake in population exposed to radiation from the Semipalatinsk nuclear test site.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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  4. Review
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  6. Observational
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Voravech NissaisorakarnDivision of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States.
George OrmsethDivision of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States.
William EarleDivision of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States.
Martha Catalina Morales-AlvarezDivision of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States.
Swapnil HiremathDivision of Nephrology, Department of Medicine, University of Ottawa and the Ottawa Hospital, Ottawa, Ontario, Canada.
Stephen P JuraschekDivision of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States.ORCID 0000-0003-4168-2696
Beth Israel Deaconess Medical Center · USUniversity of Ottawa · CA

Funding

Effects of DASH Groceries on Blood Pressure in Black Residents of Urban Food DesertsR01MD016068 · NIMHD · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STEPHEN P JURASCHEK · 2022 to 2026
$4.3M
The Effects of the DASH Diet and Sodium Reduction on Subclinical Cardiac DamageR21HL144876 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2018 to 2019
$263k
NHLBI NIH HHS R21 HL144876NIMHD NIH HHS R01 MD016068
6 · The paper itself

Abstract

Hypertension is among the most prevalent medical conditions globally and a major contributor to chronic kidney disease, cardiovascular disease, and death. Prevention through nonpharmacological, population-level interventions is critically needed to halt this worldwide epidemic. However, there are ongoing disagreements as to where public policy efforts should focus. Recently the Salt Substitute and Stroke Study demonstrated the efficacy of substituting table salt with potassium salt to reduce the risk of stroke, major cardiovascular events, and death. However, this sparked debate over whether sodium or potassium should be prioritized in countries where table salt substitution was less feasible. In this commentary, we summarize arguments in favor of either strategy: reduced sodium or increased potassium intake. Moreover, we discuss evidence and policy approaches related to either or combined approaches relevant to cultural context. Ultimately, there is an urgent need for policies that both reduce sodium and increase potassium intake; however, identifying a strategy that fits cultural context will be key to improve population-wide blood pressures.

Indexed as

HypertensionStrokeBlood PressureHumansPotassiumSodiumSodium Chloride, DietaryPotassiumSodiumSodium Chloride, Dietaryblood pressurehypertensionpotassium supplementsalt replacementsodium reduction

Identifiers

PMID37262087
PMCPMC11905867
OpenAlexW4378976378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.