Evidence map›Paper›PMID 37262062›Full record

ArticlePloS one2023

Development of diagnostic and point of care assays for a gammaherpesvirus infecting koalas.

Belinda R Wright, Martina Jelocnik, Andrea Casteriano, Yasmine S S Muir, Alistair R Legione, Paola K Vaz, Joanne M Devlin, Damien P Higgins

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Koala Conservation: The Utility of Art and Genome Banking.Advances in experimental medicine and biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Belinda R WrightKoala Health Hub, Sydney School of Veterinary Science, University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-3317-8185
Martina JelocnikCentre for Bioinnovation, University of The Sunshine Coast, Sippy Downs, Queensland, Australia.
Andrea CasterianoKoala Health Hub, Sydney School of Veterinary Science, University of Sydney, Camperdown, New South Wales, Australia.
Yasmine S S MuirKoala Health Hub, Sydney School of Veterinary Science, University of Sydney, Camperdown, New South Wales, Australia.
Alistair R LegioneAsia Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0003-2407-4496
Paola K VazAsia Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Parkville, Victoria, Australia.
Joanne M DevlinAsia Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Parkville, Victoria, Australia.
Damien P HigginsKoala Health Hub, Sydney School of Veterinary Science, University of Sydney, Camperdown, New South Wales, Australia.
The University of Sydney · AUThe University of Melbourne · AUUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent listing of koala populations as endangered across much of their range has highlighted the need for better management interventions. Disease is a key threat to koala populations but currently there is no information across the threatened populations on the distribution or impact of a gammaherpesvirus, phascolarctid gammaherpesvirus 1 (PhaHV-1). PhaHV-1 is known to infect koalas in southern populations which are, at present, not threatened. Current testing for PhaHV-1 involves lengthy laboratory techniques that do not permit quantification of viral load. In order to better understand distribution, prevalence and impacts of PhaHV-1 infections across koala populations, diagnostic and rapid point of care tests are required. We have developed two novel assays, a qPCR assay and an isothermal assay, that will enable researchers, clinicians and wildlife managers to reliably and rapidly test for PhaHV-1 in koalas. The ability to rapidly diagnose and quantify viral load will aid quarantine practices, inform translocation management and guide research into the clinical significance and impacts of PhaHV-1 infection in koalas.

Indexed as

GammaherpesvirinaePhascolarctidaeAnimalsAnimals, WildPoint-of-Care SystemsPrevalence

Identifiers

PMID37262062
PMCPMC10234535
OpenAlexW4378977414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.