Evidence map›Paper›PMID 37261533›Full record

ArticleLangenbeck's archives of surgery2023

Surgical outcomes in pelvic exenteration for advanced and recurrent malignancy: a high volume single institution experience.

Lucas De Crignis, Aurélien Dupré, Pierre Meeus, Patrice Peyrat, Michel Rivoire

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In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucas De CrignisDepartment of Surgical Oncology, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, France. lucas.decrignis@lyon.unicancer.fr.ORCID http://orcid.org/0000-0003-1554-3107
Aurélien DupréDepartment of Surgical Oncology, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, France.
Pierre MeeusDepartment of Surgical Oncology, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, France.
Patrice PeyratDepartment of Surgical Oncology, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, France.
Michel RivoireDepartment of Surgical Oncology, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePelvic exenteration remains the only curative treatment for advanced pelvic malignancies. However, identification of predictive factors for successful surgical outcomes is still a controversial issue at present time.

methodsThis retrospective study included data from all adult patients with colorectal or anal advanced pelvic malignancy registered for pelvic exenteration at the Leon Berard Cancer Center (Lyon, France). The primary endpoint was the surgical outcomes and aimed to define the predictive factors for postoperative complications. Secondary endpoints included overall survival and progression free survival in patients having experienced pelvic exenteration (PE).

resultsData from 141 patients with locally advanced tumor (N = 81) or recurrent malignancies (N = 60) diagnosed between May 1994 and November 2018 were collected. The median age was 63.3 years (95%CI 20.0-92.0). Malignancies included different locations (rectal: 69.5%, left colon: 17.0% and anal: 13.5%). Posterior pelvectomy was the most frequent surgery (81.6%). The median length of hospital stay was 23.3 days (95%CI 3.0-82.0). The major complication rate at 30 days was 24.8% and 38.1% at 90 days. The median overall survival was 54.5 months (95%CI 41.5-104.1) and the median PFS was 34.5 months (95%CI 19.6-NA).

conclusionIn selected patients, pelvic exenteration is associated with good surgical and survival outcomes.

Indexed as

CarcinomaPelvic ExenterationPelvic NeoplasmsRectal NeoplasmsAdultHumansMiddle AgedNeoplasm Recurrence, LocalPostoperative ComplicationsRetrospective StudiesTreatment OutcomeLocally advancedPelvic malignanciesSurgical outcomesSurvival outcomes

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What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.