Evidence map›Paper›PMID 37261350›Full record

ArticleFrontiers in immunology2023

Dendritic cell activation and cytokine response in vaccine breakthrough TBE patients after

Miša Marušić, Andreja Nataša Kopitar, Miša Korva, Nataša Knap, Petra Bogovič, Franc Strle, Alojz Ihan, Tatjana Avšič-Županc

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Tick-Borne Encephalitis (TBE): From Tick to Pathology.Journal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Miša MarušićLaboratory for Diagnostics of Zoonoses and World Health Organisation (WHO) Center, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Andreja Nataša KopitarLaboratory for Cellular Immunology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Miša KorvaLaboratory for Diagnostics of Zoonoses and World Health Organisation (WHO) Center, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Nataša KnapLaboratory for Diagnostics of Zoonoses and World Health Organisation (WHO) Center, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Petra BogovičDepartment of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia.
Franc StrleDepartment of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia.
Alojz IhanLaboratory for Cellular Immunology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Tatjana Avšič-ŽupancLaboratory for Diagnostics of Zoonoses and World Health Organisation (WHO) Center, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
University of Ljubljana · SILjubljana University Medical Centre · SI

Funding

World Health Organization 001
6 · The paper itself

Abstract

Tick-borne encephalitis (TBE) is a viral infection of the human central nervous system caused by the TBE virus (TBEV). The most effective protective measure against TBE is vaccination. Despite the highly immunogenic vaccine, cases of vaccine breakthroughs (VBTs) occur. One of the first targets of infection is dendritic cells (DC), which represent a fundamental bridge between innate and adaptive immunity through antigen presentation, costimulation, and cytokine production. Therefore, we investigated the activation and maturation of DCs and cytokine production after

Indexed as

Encephalitis, Tick-BorneViral VaccinesCytokinesDendritic CellsHumansInterleukin-12Leukocytes, MononuclearCytokinesInterleukin-12Viral Vaccinescytokinesdendritic cellsimmune response in vitrotick-borne encephalitisvaccine breakthrough

Identifiers

PMID37261350
PMCPMC10228714
OpenAlexW4376890755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.