Evidence map›Paper›PMID 37261268›Full record

ArticleSarcoma2023

Accuracy of Time to Treatment Initiation Data in Musculoskeletal Soft Tissue Sarcoma.

Joshua M Lawrenz, Jose F Vega, Jaiben George, Gannon L Curtis, Jaymeson Gordon, Amanda Maggiotto, Katherine Tullio, Dale R Shepard, John D Reith, Herbert S Schwartz and 2 more

Abstract read
In one paragraph

Article in Sarcoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joshua M LawrenzDepartment of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID https://orcid.org/0000-0003-4069-7044
Jose F VegaDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.
Jaiben GeorgeDepartment of Orthopaedic Surgery, AIIMS Hospital, New Delhi, India.
Gannon L CurtisDepartment of Urology, University Health Center, Wayne State University, Detroit, MI 48201, USA.
Jaymeson GordonCase Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Amanda MaggiottoTaussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA.
Katherine TullioTaussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA.
Dale R ShepardTaussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA.
John D ReithDepartment of Pathology, Cleveland Clinic, Cleveland, OH 44195, USA.
Herbert S SchwartzDepartment of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Lukas M NystromDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.
Nathan W MeskoDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Time to treatment initiation (TTI) is a quality metric in cancer care. The purpose of this study is to determine the accuracy of TTI data from a single cancer center registry that reports to the National Cancer Database (NCDB) for sarcoma diagnoses. Methods: A retrospective analysis of a single Commission on Cancer (CoC)-accredited cancer center's tumor registry between 2006 and 2016 identified 402 patients who underwent treatment of a musculoskeletal soft tissue sarcoma and had TTI data available. Registry-reported TTI was extracted from the tumor registry. Effective TTI was manually calculated by medical record review as the number of days from the date of tissue diagnosis to initiation of first effective treatment. Effective treatment was defined as oncologic surgical excision or initiation of radiation therapy or chemotherapy. Registry-reported TTI and effective TTI values were compared for concordance in all patients. Results: In the entire cohort, 25% (99/402) of patients had TTI data discordance, all related to surgical treatment definition. For patients with a registry-reported value of TTI = 0 days, 74% (87/118) had a diagnostic surgical procedure coded as their first treatment event, with 73 unplanned incomplete excision procedures and 14 incisional biopsies. In these patients, effective TTI was on average 59 days ( Conclusions: Nearly three-fourths of patients with a registry-reported value of TTI = 0 days in a large, CoC-accredited cancer center registry had a diagnostic procedure coded as their first treatment event, though their effective treatment had not yet started. These data suggest that TTI is likely longer than what is reported to the NCDB. Redefinition of what constitutes surgical treatment should be considered to improve the accuracy of data used in measuring TTI in sarcoma.

Identifiers

PMID37261268
PMCPMC10229237

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.