Evidence map›Paper›PMID 37261214›Full record

ArticleThe Lancet regional health. Europe2023

Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls.

Bang Zheng, Giulia Vivaldi, Luke Daines, Olivia C Leavy, Matthew Richardson, Omer Elneima, Hamish J C McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno and 27 more

Abstract read
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In one paragraph

Article in The Lancet regional health. Europe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Trends in long COVID among US adults, 2022-2024.Frontiers in public health · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.International journal of epidemiology · 2024
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Bang ZhengUsher Institute, University of Edinburgh, Edinburgh, UK.
Giulia VivaldiBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Luke DainesUsher Institute, University of Edinburgh, Edinburgh, UK.
Olivia C LeavyDepartment of Population Health Sciences, University of Leicester, Leicester, UK.
Matthew RichardsonThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Omer ElneimaThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Hamish J C McAuleyThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Aarti ShikotraNIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Amisha SingapuriThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Marco SerenoThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Ruth M SaundersThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Victoria C HarrisThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Linzy Houchen-WolloffCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Neil J GreeningThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Paul E PfefferBarts Health NHS Trust, London, UK.
John R HurstUCL Respiratory, University College London, London, UK.
Jeremy S BrownUCL Respiratory, University College London, London, UK.
Manu Shankar-HariCentre for Inflammation Research, University of Edinburgh, Edinburgh, UK.
Carlos EchevarriaThe Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.
Anthony De SoyzaThe Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.
Ewen M HarrisonCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
Annemarie B DochertyCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
Nazir LoneUsher Institute, University of Edinburgh, Edinburgh, UK.
Jennifer K QuintNational Heart Lung Institute, Imperial College London, London, UK.
James D ChalmersUniversity of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Ling-Pei HoMedical Research Council (MRC) Human Immunology Unit, University of Oxford, Oxford, UK.
Alex HorsleyDivision of Infection, Immunity & Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Michael MarksDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
Krishna PoinasamyAsthma and Lung UK, London, UK.
Betty RamanRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Liam G HeaneyWellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.
Louise V WainDepartment of Population Health Sciences, University of Leicester, Leicester, UK.
Rachael A EvansThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Christopher E BrightlingThe Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Adrian MartineauBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Aziz SheikhUsher Institute, University of Edinburgh, Edinburgh, UK.
PHOSP-COVID Study Collaborative Group

Funding

British Heart Foundation CH/16/1/32013British Heart Foundation SP/17/16/33519Medical Research Council MC_PC_20031Medical Research Council MC_PC_20060Medical Research Council MR/S004041/1Medical Research Council MR/V040162/1Medical Research Council MR/W006111/1Wellcome Trust 206330/Z/17/ZWellcome Trust 209553/Z/17/Z
6 · The paper itself

Abstract

Background: The risk factors for recovery from COVID-19 dyspnoea are poorly understood. We investigated determinants of recovery from dyspnoea in adults with COVID-19 and compared these to determinants of recovery from non-COVID-19 dyspnoea. Methods: We used data from two prospective cohort studies: PHOSP-COVID (patients hospitalised between March 2020 and April 2021 with COVID-19) and COVIDENCE UK (community cohort studied over the same time period). PHOSP-COVID data were collected during hospitalisation and at 5-month and 1-year follow-up visits. COVIDENCE UK data were obtained through baseline and monthly online questionnaires. Dyspnoea was measured in both cohorts with the Medical Research Council Dyspnoea Scale. We used multivariable logistic regression to identify determinants associated with a reduction in dyspnoea between 5-month and 1-year follow-up. Findings: We included 990 PHOSP-COVID and 3309 COVIDENCE UK participants. We observed higher odds of improvement between 5-month and 1-year follow-up among PHOSP-COVID participants who were younger (odds ratio 1.02 per year, 95% CI 1.01-1.03), male (1.54, 1.16-2.04), neither obese nor severely obese (1.82, 1.06-3.13 and 4.19, 2.14-8.19, respectively), had no pre-existing anxiety or depression (1.56, 1.09-2.22) or cardiovascular disease (1.33, 1.00-1.79), and shorter hospital admission (1.01 per day, 1.00-1.02). Similar associations were found in those recovering from non-COVID-19 dyspnoea, excluding age (and length of hospital admission). Interpretation: Factors associated with dyspnoea recovery at 1-year post-discharge among patients hospitalised with COVID-19 were similar to those among community controls without COVID-19. Funding: PHOSP-COVID is supported by a grant from the MRC-UK Research and Innovation and the Department of Health and Social Care through the National Institute for Health Research (NIHR) rapid response panel to tackle COVID-19. The views expressed in the publication are those of the author(s) and not necessarily those of the National Health Service (NHS), the NIHR or the Department of Health and Social Care.COVIDENCE UK is supported by the UK Research and Innovation, the National Institute for Health Research, and Barts Charity. The views expressed are those of the authors and not necessarily those of the funders.

Indexed as

CohortCOVID-19DyspnoeaLong COVIDRecovery

Identifiers

PMID37261214
PMCPMC10145209

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.