Evidence map›Paper›PMID 37261191›Full record

ArticleVascular and endovascular review2022

A Clinical Trial of Venous Stent Placement for Post-thrombotic Syndrome: Current Status and Pandemic-related Changes.

Suresh Vedantham, Sameer Parpia, Susan R Kahn

Open access · goldAbstract read
In one paragraph

Article in Vascular and endovascular review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Suresh VedanthamMallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, US.ORCID 0000-0002-5734-7553
Sameer ParpiaDepartments of Oncology, and Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-9407-5622
Susan R KahnFaculty of Medicine and Health Sciences, McGill University, Montreal, Canada.ORCID 0000-0002-5667-8916
Impact · CAMallinckrodt (United States) · USMcGill University Health Centre · CA

Funding

1/2 CATHETER-DIRECTED THERAPY FOR CHRONIC DVT (C-TRACT TRIAL)UH3HL138325 · NHLBI · WASHINGTON UNIVERSITY · PI VEDANTHAM, SURESH · 2018 to 2023
$8.1M
2/2 Catheter-Directed Therapy for Chronic DVT (C-TRACT Trial)-DCCU24HL137835 · NHLBI · MCMASTER UNIVERSITY · PI PARPIA, SAMEER · 2017 to 2023
$2.1M
1/2 CATHETER-DIRECTED THERAPY FOR CHRONIC DVT (C-TRACT TRIAL)UG3HL138325 · NHLBI · WASHINGTON UNIVERSITY · PI VEDANTHAM, SURESH · 2017 to 2017
$1.4M
CHRONIC VENOUS THROMBOSIS: RELIEF WITH ADJUNCTIVE CATHETER-BASED THERAPY (C-TRACTU34HL123831 · NHLBI · WASHINGTON UNIVERSITY · PI VEDANTHAM, SURESH · 2014 to 2015
$654k
NHLBI NIH HHS U24 HL137835NHLBI NIH HHS U34 HL123831NHLBI NIH HHS UG3 HL138325NHLBI NIH HHS UH3 HL138325
6 · The paper itself

Abstract

Patients with post-thrombotic syndrome (PTS) and iliac vein obstruction have lower extremity symptoms, activity limitation and impairment of health-related quality of life. Preliminary studies suggest that iliac vein stent placement, which eliminates venous outflow obstruction, may reduce the clinical severity of PTS. However, stent placement is associated with patient risk, inconvenience and cost. Therefore, the Chronic Venous Thrombosis - Relief with Adjunctive Catheter-directed Therapy (C-TRACT) trial was launched to rigorously assess the risk-benefit ratio of stent placement for the treatment of moderate or severe PTS. In the trial, patients in both treatment groups receive a high quality of multimodality PTS care that includes medical, compressive, and ulcer therapies. Due to the COVID-19 pandemic, the trial protocol and practices were modified to enhance the study feasibility while preserving its ability to answer its primary question. This review summarises the current status of the trial and the potential impact of the pandemic-related adaptations to future venous clinical practice and research.

Indexed as

Deep vein thrombosispost-thrombotic syndromerandomised trialstent

Identifiers

PMID37261191
PMCPMC10230505
OpenAlexW4283275613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.