Evidence map›Paper›PMID 37260851›Full record

ArticleBioMed research international2023

Antiangiogenic Potential of Troxerutin and Chitosan Loaded Troxerutin on Chorioallantoic Membrane Model.

Gowtham Kumar Subbaraj, Harini Elangovan, Prema Chandramouli, Santhosh Kumar Yasam, Kirubhanand Chandrasekaran, Langeswaran Kulanthaivel, Sangavi Pandi, Senthilkumar Subramanian

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Gowtham Kumar SubbarajFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (Deemed to be University), Kelambakkam, 603 103 Tamil Nadu, India.ORCID https://orcid.org/0000-0002-0531-424X
Harini ElangovanFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (Deemed to be University), Kelambakkam, 603 103 Tamil Nadu, India.ORCID https://orcid.org/0009-0007-0069-745X
Prema ChandramouliFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (Deemed to be University), Kelambakkam, 603 103 Tamil Nadu, India.ORCID https://orcid.org/0000-0003-0181-0104
Santhosh Kumar YasamFaculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (Deemed to be University), Kelambakkam, 603 103 Tamil Nadu, India.ORCID https://orcid.org/0000-0003-1252-4138
Kirubhanand ChandrasekaranDepartment of Anatomy, All India Institute of Medical Sciences (AIIMS), Nagpur, Maharashtra, India.ORCID https://orcid.org/0000-0002-3525-2342
Langeswaran KulanthaivelCancer Genetics & Molecular Biology Laboratory, Department of Biotechnology, Science Campus, Alagappa University, Karaikudi, Tamil Nadu 630003, India.ORCID https://orcid.org/0000-0002-3154-1331
Sangavi PandiCancer Genetics & Molecular Biology Laboratory, Department of Biotechnology, Science Campus, Alagappa University, Karaikudi, Tamil Nadu 630003, India.ORCID https://orcid.org/0000-0002-6452-7632
Senthilkumar SubramanianSchool of Medicine, College of Medicine and Health Science, Jigjiga University, Ethiopia.ORCID https://orcid.org/0000-0002-5025-5939
Chettinad Academy of Research and Education · INAlagappa University · INAll India Institute of Medical Sciences, Nagpur · INJigjiga University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is crucial to the development of cancer because it allows the transport of oxygen, nutrients, and growth factors as well as the spread of tumors to distant organs. Inhibitors of angiogenesis prevent the formation of blood vessels that allow tumor cells to shrink, rather than promote tumor growth. Chitosan acts as a carrier for many drugs, since the compound has various properties such as biodegradable, less toxicity, more stable, simple, easy to prepare, and biocompatible. The aim of the current study was to evaluate the efficacy of chitosan nanoparticles encapsulated with troxerutin (Chi-Trox NPs) against angiogenesis and cancer

Indexed as

ChitosanNanoparticlesAnimalsChickensChorioallantoic MembraneFibroblast Growth Factor 2HydroxyethylrutosideRNA, MessengerVimentinChitosanFibroblast Growth Factor 2HydroxyethylrutosideRNA, MessengertroxerutinVimentin

Identifiers

PMID37260851
PMCPMC10229255
OpenAlexW4378078330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.