Evidence map›Paper›PMID 37260388›Full record

ArticleInfection and immunity2023

A Candidate Bacterial-Type Amino Acid Decarboxylase Is Essential for Male Gamete Exflagellation and Mosquito Transmission of the Malaria Parasite.

Umit Y Kina, Mohd Kamil, Gozde Deveci, Ab Matteen Rafiqi, Kai Matuschewski, Ahmed S I Aly

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Umit Y KinaAly lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.
Mohd KamilAly lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.
Gozde DeveciAly lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.
Ab Matteen RafiqiAly lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.ORCID 0000-0002-5682-1727
Kai MatuschewskiDepartment of Molecular Parasitology, Institute of Biology, Humboldt University, Berlin, Germany.
Ahmed S I AlyAly lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.ORCID 0000-0002-2049-6686
Bezmiâlem Vakıf Üniversitesi · TRHumboldt-Universität zu Berlin · DEInfectious Disease Research Institute · US

Funding

Selection of the Determinants of Plasmodium Sporozoite Infectivity and MotilityR21AI111058 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI ALY, AHMED SAYED IBRAHIM · 2015 to 2016
$426k
NIAID NIH HHS R21 AI111058
6 · The paper itself

Abstract

A frequent side effect of chemotherapy against malaria parasite blood infections is a dramatic induction of the sexual blood stages, thereby enhancing the risk of future malaria transmissions. The polyamine biosynthesis pathway has been suggested as a candidate target for transmission-blocking anti-malarial drug development. Herein, we describe the role of a bacterial-type amino acid decarboxylase (

Indexed as

Carboxy-LyasesCulicidaeMalariaParasitesAmino AcidsAnimalsBacteriaGerm CellsLysineMaleAmino AcidsCarboxy-LyasesLysineamino acid decarboxylaseblood stagesexflagellationgametesMalariamosquito transmissionPlasmodiumpolyamine

Identifiers

PMID37260388
PMCPMC10353352
OpenAlexW4378953816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.