Evidence map›Paper›PMID 37260166›Full record

ArticleTurkish journal of obstetrics and gynecology2023

Reproductive and oncologic outcomes in women with non-epithelial ovarian cancer: Single center experience over 25 years.

Saliha Sağnıç, Ceyda Karadağ, Hasan Aykut Tuncer, Selen Doğan, Tayup Şimşek

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saliha SağnıçAkdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Antalya, Turkey.ORCID 0000-0002-5440-2940
Ceyda KaradağAkdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Antalya, Turkey.ORCID 0000-0002-9557-0932
Hasan Aykut TuncerAkdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Antalya, Turkey.ORCID 0000-0002-5434-1025
Selen DoğanAkdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Antalya, Turkey.ORCID 0000-0002-4019-5581
Tayup ŞimşekAkdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Antalya, Turkey.ORCID 0000-0003-1088-3970
Akdeniz University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to present our single-center clinical experience regarding tumor clinicopathologic features, treatment modalities, and reproductive and oncologic outcomes in patients with non-epithelial ovarian cancer (NEOC) over 25 years. Materials and Methods: A total of 100 patients with clinicopathological diagnosis of NEOC who were treated at our tertiary care center between 1996 and 2022 were included in this retrospective cohort analysis study. Data on demographic, clinical and obstetric characteristics of patients at the time of initial diagnosis as well as tumor clinicopathologic features, treatment modalities, and oncological and reproductive outcomes were recorded. Results: NEOCs involved germ cell tumors (GCTs) in 46 (46%) patients and sex cordstromal tumors (SCSTs) in 54 (54%) patients. Thirty patients with GCTs and thirty-four patients with SCSTs possessed histological subtypes with malignant features. Most patients with GCTs (37%) and SCSTs (55.6%) had FIGO Stage 1 disease at the time of initial diagnosis. Overall, 76.6% of patients in the GCT group (n=23) underwent fertility-sparing surgery (FSS), while 76.5% of the patients in the SCST group (n=26) were treated with non-fertility-sparing surgical procedures. All patients who underwent FSS and had a recurrence in their follow-up (n=4) was stage 3 patients. Seven out of 10 patients (2 patients at stage 3 and 5 patients at stage 1) who desired pregnancy delivered between 38 and 40 gestational weeks without any congenital anomaly. The prognosis was excellent in both groups, with 5-year overall survival (OS) rates of 93.5% in GCTs and 96.3% in SCST groups. The 5-year disease-free survival was 89.1% in GCTs and 94.4% in SCSTs. FSS was not associated with worse oncologic outcomes. Conclusion: NEOCs usually have a good prognosis because they are detected at an early stage. FSS may be indicated for women of reproductive age with early-stage NEOCs.

Indexed as

Disease-free survivalfertilitynon-epithelial ovarian tumorprognosis

Identifiers

PMID37260166
PMCPMC10236224
OpenAlexW4378953797

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.