Evidence map›Paper›PMID 37259861›Full record

Observational studyCirculation. Cardiovascular interventions2023

Interventional Versus Conservative Strategy in Patients With Spontaneous Coronary Artery Dissections: Insights From DISCO Registry.

Stefano Benenati, Federico Giacobbe, Antonio Zingarelli, Fernando Macaya, Carloalberto Biolè, Angelica Rossi, Marco Pavani, Giorgio Quadri, Umberto Barbero, Andrea Erriquez and 13 more

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in Circulation. Cardiovascular interventions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04415762 (A Multicenter Italian and Spanish Observational Registry on Patients Affected by Spontaneous Coronary Artery Dissection), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04415762 completednot on this map

A Multicenter Italian and Spanish Observational Registry on Patients Affected by Spontaneous Coronary Artery Dissection (SCAD)

TypeobservationalSponsorSan Luigi Gonzaga HospitalRan2009 to 2019Enrolled314ConditionsSpontaneous Coronary Artery Dissection
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Spontaneous Coronary Artery Dissection in Women.Reviews in cardiovascular medicine · 2025
    Article
  10. Article
  11. Review
  12. Swine Model of Coronary Artery Dissection.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 12 institutions in 3 countries.

Stefano Benenati *University of Genoa, Italy (S.B., I.P.).ORCID 0000-0001-9669-4278
Federico Giacobbe *Cardiology Department, AOU Citta` della Salute e della Scienza di Torino, Turin, Italy (F.G.).ORCID 0000-0002-1176-4300
Antonio ZingarelliCardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiology Network, Genova, Italy (A.Z., I.P.).ORCID 0000-0002-8240-2622
Fernando MacayaHospital Clínico San Carlos, IdiSSC, Universidad Complutense de Madrid, Spain (F.M., N.G., J.E.).ORCID 0000-0003-1770-3004
Carloalberto BiolèDivision of Cardiology, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy (C.B., A.C.).
Angelica RossiDivision of Cardiology, Azienda Ospedaliera Brotzu, Cagliari, Italy (A.R.).
Marco PavaniInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Infermi Hospital, Italy (M.P., C.R., G.M., F.V., E.C.).
Giorgio QuadriDivision of Cardiology, Ordine Ospedale Mauriziano Umberto I, Torino (TO), Italy (G.Q., T.A.).
Umberto BarberoDivision of Cardiology Ospedale Maggiore Ss. Annunziata - Savigliano (CN), Italy (U.B.).
Andrea ErriquezDivision of Cardiology, University of Ferrara, Italy (A.E.).
Tiziana AranzullaDivision of Cardiology, Ordine Ospedale Mauriziano Umberto I, Torino (TO), Italy (G.Q., T.A.).
Chiara CavallinoDivision of Cardiology, Sant'Andrea Hospital, Vercelli, Italy (C.C.).
Dario BuccheriInterventional Cardiology Unit, Department of Cardiology, S. Antonio Abate Hospital, Trapani, Italy (D.B.).
Cristina RolfoInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Infermi Hospital, Italy (M.P., C.R., G.M., F.V., E.C.).
Giuseppe PattiUniversity of Eastern Piedmont, Department of Thoracic and Cardiovascular Diseases, Maggiore della Carità Hospital, Novara, Italy (G.P.).ORCID 0000-0002-5404-3968
Nieves GonzaloHospital Clínico San Carlos, IdiSSC, Universidad Complutense de Madrid, Spain (F.M., N.G., J.E.).ORCID 0000-0003-3827-945X
Alessandra ChinagliaDivision of Cardiology, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy (C.B., A.C.).
Giuseppe MusumeciInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Infermi Hospital, Italy (M.P., C.R., G.M., F.V., E.C.).
Javier EscanedHospital Clínico San Carlos, IdiSSC, Universidad Complutense de Madrid, Spain (F.M., N.G., J.E.).ORCID 0000-0003-4932-0112
Ferdinando VarbellaInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Infermi Hospital, Italy (M.P., C.R., G.M., F.V., E.C.).
Enrico Cerrato *Interventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Infermi Hospital, Italy (M.P., C.R., G.M., F.V., E.C.).ORCID 0000-0002-1260-7534
Italo Porto *University of Genoa, Italy (S.B., I.P.).ORCID 0000-0002-9854-5046
DISCO Collaborators
Ospedale San Luigi Gonzaga · ITHospital Clínico San Carlos · ESA. O. Ordine Mauriziano di Torino · ITOspedale Policlinico San Martino · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera G. Brotzu · ITCTO Andrea Alesini · ITOspedale Sant Antonio · ITOspedale SS. Annunziata · ITPiedmont University · USUniversity of Ferrara · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal management of patients with spontaneous coronary artery dissection remains debated.

methodsPatients enrolled in the DISCO (Dissezioni Spontanee Coronariche) Registry up to December 2020 were included. The primary end point was major adverse cardiovascular events, a composite of all-cause death, nonfatal myocardial infarction, and repeat percutaneous coronary intervention (PCI). Independent predictors of PCI and medical management were investigated.

resultsAmong 369 patients, 129 (35%) underwent PCI, whereas 240 (65%) were medically managed. ST-segment-elevation myocardial infarction (68% versus 35%,

conclusionsClinical presentation and procedural variables drive the choice of the initial therapeutic approach in spontaneous coronary artery dissection. If PCI is needed, it seems to be associated with a similar risk of short-to-mid-term adverse events compared to medical treatment. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT04415762.

Indexed as

Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionConservative TreatmentCoronary AngiographyCoronary VesselsHumansRisk FactorsTreatment Outcomecoronary artery dissection, spontaneousmyocardial infarctionpercutaneous coronary interventionstents

Identifiers

PMID37259861
PMCPMC10810347
OpenAlexW4378952728

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.