Evidence map›Paper›PMID 37259667›Full record

ArticleJournal of musculoskeletal & neuronal interactions2023

Severe hypocalcemia after denosumab administration in a patient with chronic kidney disease: a case report.

Eleni Kouroglou, Vasiliki Tsiama, Sofia Dionysopoulou, Georgios Gavriiloglou, Margarita Bora, Konstantinos Belis, Stella Proikaki, Christos Savvidis, Panagiota Giannou, Dimitrios Petras

Abstract readCase Reports
PubMed Full text at PMC
In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eleni Kouroglou *Endocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Vasiliki Tsiama *Endocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Sofia DionysopoulouEndocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Georgios GavriiloglouEndocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Margarita BoraNephrology Department, Hippocration Hospital, Athens, Greece.
Konstantinos BelisEndocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Stella ProikakiEndocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Christos SavvidisEndocrinology and Metabolism Department, Hippocration Hospital, Athens, Greece.
Panagiota GiannouNephrology Department, Hippocration Hospital, Athens, Greece.
Dimitrios PetrasNephrology Department, Hippocration Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with altered kidney function are at increased risk of hypocalcemia after denosumab administration. There is however a small number of studies and case reports describing hypocalcemia refractory to treatment. We describe a case of severe hypocalcemia, after the administration of three doses of denosumab, in a young patient with lupus nephritis under corticosteroid coverage and osteopenia. However, more studies are needed in order to extract a safe conclusion about the factors that contribute to the development of severe hypocalcemia in this group of patients.

Indexed as

Bone Density Conservation AgentsHypocalcemiaOsteoporosisRenal Insufficiency, ChronicCalciumDenosumabHumansBone Density Conservation AgentsCalciumDenosumabBonesCalciumDenosumabHypocalcemia

Identifiers

PMID37259667
PMCPMC10233229

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.