ArticleRenal failure2023
Association of dietary total antioxidant capacity with all-cause and cardiovascular mortality in patients with chronic kidney disease: based on two retrospective cohort studies of NHANES.
Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- Dietary antioxidants and CKM-depression comorbidity: a primary analysis with a secondary evaluation of all-cause mortality using six machine learning algorithms.European journal of medical research · 2025Observational
- Composite dietary antioxidant index is inversely associated with all-cause, cardiovascular and cancer mortality in adults with hyperlipidemia.Scientific reports · 2025Article
- The Clinical Utility and Plausibility of Oxidative and Antioxidant Variables in Chronic and End-Stage Kidney Disease: A Review of the Literature.International journal of molecular sciences · 2025Review
- Associations of composite dietary antioxidant index with premature death and all-cause mortality: a cohort study.BMC public health · 2025Article
- Association of composite dietary antioxidant index with mortality risk among adults with chronic kidney disease in NHANES.Scientific reports · 2025Article
- Association of Composite Dietary Antioxidant Index With the Risk of Nonalcoholic Fatty Liver Disease and All-Cause and Cause-Specific Mortality: Evidence From NHANES 2001-2018.International journal of endocrinology · 2025Article
- Association of dietary inflammatory index, composite dietary antioxidant index and risk of death among adult cancer survivors: findings from the National Health and Nutrition Examination Survey 2001-2018.Frontiers in immunology · 2025Article
- Sex differences in the association between composite dietary antioxidant index and hyperlipidemia: Insights from NHANES.PloS one · 2025Article
- Relationship between different diet indices and frailty and mortality in population with CKD.Frontiers in nutrition · 2025Article
- Composite dietary antioxidant index, chronic respiratory disease, and all-cause mortality: National Health and Nutrition Examination Survey, 2003-2018.European journal of nutrition · 2024Article
- Association of dietary antioxidant indices with kidney function indicators in patients with type 2 diabetes: a cross-sectional study.Scientific reports · 2024Article
- Dietary antioxidant and inflammatory potential in asthmatic patients and its association with all-cause mortality.Nutrition journal · 2024Article
- Association of composite dietary antioxidant index with cardiovascular disease in adults: results from 2011 to 2020 NHANES.Frontiers in cardiovascular medicine · 2024Article
- Association of composite dietary antioxidant index with mortality in adults with hypertension: evidence from NHANES.Frontiers in nutrition · 2024Article
- The association between dietary antioxidant quality score and uric acid related mortality in patients with chronic kidney disease.Frontiers in nutrition · 2024Article
- Association of the oxidative balance score and chronic kidney disease: insights from the national health and nutrition examination survey 2009-2018.Frontiers in nutrition · 2024Article
- Association between dietary antioxidant levels and chronic obstructive pulmonary disease: a mediation analysis of inflammatory factors.Frontiers in immunology · 2023Article
- Physical activity modifies the association of the composite dietary antioxidant index with all-cause mortality in the US osteoarthritis population.Frontiers in public health · 2023Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between dietary total antioxidant capacity (DTAC) and death risk among CKD populations remains unclear.
methodsBased on vitamin C equivalent antioxidant capacity (VCEAC) and the component dietary antioxidant index (CDAI) indices, we analyzed two cohorts to investigate the association of DTAC with all-cause and CVD mortality in CKD patients using data from National Health and Nutrition Examination Survey (2007-2018). VCEAC (
resultsOur results showed L-shaped associations of DTAC with all-cause mortality among individuals with CKD stages 1-2 in both cohorts. Compared to the lowest quartile, higher dietary total antioxidant intake was associated with lower all-cause mortality risks among CKD stages 1-2 after adjustment for covariates, with HRs (95%CI) of 1.00, 0.91 (0.71,1.17), 0.69 (0.53,0.90), and 0.70 (0.54,0.91) in VCEAC, and similar respective estimate trends in CDAI. After sensitivity and subgroup analyses, there were no benefits for patients with stage 3-5 CKD or albuminuria. Mediation analysis revealed that the proportions mediated in both cohorts were less consistent.
conclusionsModerate dietary total antioxidants intake has potential benefits for early-stage CKD patients. However, further evidence is needed to confirm whether patients with worsening CKD can benefit in the long term.
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