Evidence map›Paper›PMID 37259389›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

The Use of Calcium Phosphate-Based Starter Pellets for the Preparation of Sprinkle IR MUPS Formulation of Rosuvastatin Calcium.

Krzysztof Cal, Barbara Mikolaszek, Tobias Hess, Markos Papaioannou, Joanna Lenik, Patrycja Ciosek-Skibińska, Helene Wall, Jadwiga Paszkowska, Svitlana Romanova, Grzegorz Garbacz and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pharmaceutically engineered olfactory-masking agents: Innovating oral drug delivery through multisensory excipient design.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Krzysztof CalDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Gdansk, al. Gen. J. Hallera 107, 80-416 Gdansk, Poland.ORCID 0000-0001-9994-5626
Barbara MikolaszekDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Gdansk, al. Gen. J. Hallera 107, 80-416 Gdansk, Poland.ORCID 0000-0001-5894-7705
Tobias HessChemische Fabrik Budenheim KG, Rheinstrasse 27, 55257 Budenheim, Germany.ORCID 0000-0002-3950-9010
Markos PapaioannouChemische Fabrik Budenheim KG, Rheinstrasse 27, 55257 Budenheim, Germany.
Joanna LenikDepartment of Analytical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, M. Curie-Skłodowska Sq. 3, 20-031 Lublin, Poland.
Patrycja Ciosek-SkibińskaChair of Medical Biotechnology, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.
Helene WallHarke Pharma GmbH, Xantener Straße 1, 45479 Mülheim an der Ruhr, Germany.
Jadwiga PaszkowskaPhysiolution Polska sp. z o.o., Skarbowcow 81/7, 53-025 Wroclaw, Poland.ORCID 0000-0003-1230-8128
Svitlana RomanovaPhysiolution Polska sp. z o.o., Skarbowcow 81/7, 53-025 Wroclaw, Poland.
Grzegorz GarbaczPhysiolution Polska sp. z o.o., Skarbowcow 81/7, 53-025 Wroclaw, Poland.
Daniel ZakowieckiDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Gdansk, al. Gen. J. Hallera 107, 80-416 Gdansk, Poland.ORCID 0000-0003-3935-4263

Funding

Gdańsk Medical University 01-0517/08/510National Science Centre, Poland UMO-2018/30/E/ST4/00481
6 · The paper itself

Abstract

Sprinkle formulations represent an interesting concept of medicinal products aimed at the steadily growing population of patients suffering from swallowing difficulties (dysphagia). In the present work, immediate-release sprinkle MUPS (multiple-unit pellet system) containing rosuvastatin calcium as a model drug substance was successfully developed. The formulation was prepared by drug layering technique using novel calcium phosphate-based starting pellets (PharSQ

Indexed as

calcium phosphate-based pelletsMUPSrosuvastatin calciumsprinkle formulations

Identifiers

PMID37259389
PMCPMC9958699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.