Evidence map›Paper›PMID 37259336›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene.

Julyanne Maria Saraiva de Sousa, Thaís Amanda de Lima Nunes, Raiza Raianne Luz Rodrigues, João Paulo Araújo de Sousa, Maria da Conceição Albuquerque Val, Francisco Alex da Rocha Coelho, Airton Lucas Sousa Dos Santos, Nicolle Barreira Maciel, Vanessa Maria Rodrigues de Souza, Yasmim Alves Aires Machado and 7 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Essential Oil ofPlants (Basel, Switzerland) · 2026
    Review
  8. Exploring Aroma and Flavor Diversity inMolecules (Basel, Switzerland) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Engineering3 Biotech · 2023
    Article
  15. Analysis of Volatile Components inMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Julyanne Maria Saraiva de SousaLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Thaís Amanda de Lima NunesLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Raiza Raianne Luz RodriguesLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
João Paulo Araújo de SousaLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Maria da Conceição Albuquerque ValLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.ORCID 0000-0003-4643-8350
Francisco Alex da Rocha CoelhoLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.ORCID 0000-0002-3308-375X
Airton Lucas Sousa Dos SantosLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Nicolle Barreira MacielLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Vanessa Maria Rodrigues de SouzaLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Yasmim Alves Aires MachadoLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.
Paulo Sérgio de Araújo SousaResearch Group on Medicinal Chemistry and Biotechnology, Federal University of Maranhão, São Bernardo 65550-000, MA, Brazil.
Alyne Rodrigues de AraújoResearch Center in Biodiversity and Biotechnology, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.ORCID 0000-0002-2801-1401
Jefferson Almeida RochaResearch Group on Medicinal Chemistry and Biotechnology, Federal University of Maranhão, São Bernardo 65550-000, MA, Brazil.ORCID 0000-0001-6619-2293
Damião Pergentino de SousaLaboratory of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, Campus I, Federal University of Paraiba, João Pessoa 58051-900, PB, Brazil.
Marcos Vinicius da SilvaLaboratory of Immunology and Parasitology, Institute of Biological and Natural Sciences, Federal University of Triângulo Mineiro, Uberaba 38025-180, MG, Brazil.ORCID 0000-0002-2966-7621
Daniel Dias Rufino ArcanjoDepartment of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil.ORCID 0000-0001-7021-2744
Klinger Antônio da Franca RodriguesLaboratory of Infectious Diseases, Campus Ministro Reis Velloso, Parnaíba Delta Federal University, Parnaíba 64202-020, PI, Brazil.ORCID 0000-0003-3904-3529
Universidade Federal do Maranhão · BRUniversidade Federal da Paraíba · BRUniversidade Federal do Piauí · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

Fundação de Amparo à Pesquisa do Estado do Piauí 010/2021National Council for Scientific and Technological Development 403260/2021-3
6 · The paper itself

Abstract

Leishmaniasis is a group of infectious-parasitic diseases with high mortality rates, and endemic in many regions of the globe. The currently available drugs present serious problems such as high toxicity, costs, and the emergence of drug resistance. This has stimulated research into new antileishmania drugs based on natural products and their derivatives. β-Ocimene is a monoterpene found naturally in the essential oils of many plant species which presents antileishmanial activity, and which has not yet been evaluated for its potential to inhibit the etiological agent of leishmaniasis. The aim of this work was to evaluate the activity of β-ocimene against

Indexed as

antileishmanialcytotoxicityL. amazonensisoxidativeβ-ocimene

Identifiers

PMID37259336
PMCPMC9960243
OpenAlexW4318199989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.