Evidence map›Paper›PMID 37258534›Full record

ArticleNature communications2023

Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence.

Nir Moneta, Mona M Garvert, Hauke R Heekeren, Nicolas W Schuck

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Prefrontal Mechanisms of Rule Learning.bioRxiv : the preprint server for biology · 2026
    Article
  7. Entorhinal Cortex Signals Dimensions of Past Experience That Can Be Generalized in a Novel Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Review
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  11. Article
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  15. Article
  16. Revisiting the role of computational neuroimaging in the era of integrative neuroscience.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  17. Adaptive Safety Coding in the Prefrontal Cortex.bioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nir MonetaMax Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany. moneta@mpib-berlin.mpg.de.ORCID 0000-0001-6125-4117
Mona M GarvertMax Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany.
Hauke R HeekerenEinstein Center for Neurosciences Berlin, Charité Universitätsmedizin Berlin, 10117, Berlin, Germany.
Nicolas W SchuckMax Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany. schuck@mpib-berlin.mpg.de.ORCID 0000-0002-0150-8776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ventromedial prefrontal-cortex (vmPFC) is known to contain expected value signals that inform our choices. But expected values even for the same stimulus can differ by task. In this study, we asked how the brain flexibly switches between such value representations in a task-dependent manner. Thirty-five participants alternated between tasks in which either stimulus color or motion predicted rewards. We show that multivariate vmPFC signals contain a rich representation that includes the current task state or context (motion/color), the associated expected value, and crucially, the irrelevant value of the alternative context. We also find that irrelevant value representations in vmPFC compete with relevant value signals, interact with task-state representations and relate to behavioral signs of value competition. Our results shed light on vmPFC's role in decision making, bridging between its role in mapping observations onto the task states of a mental map, and computing expected values for multiple states.

Indexed as

Magnetic Resonance ImagingPrefrontal CortexBrain MappingChoice BehaviorHumansReward

Identifiers

PMID37258534
PMCPMC10232498

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.