Evidence map›Paper›PMID 37258516›Full record

ArticleScientific reports2023

Automated LVO detection and collateral scoring on CTA using a 3D self-configuring object detection network: a multi-center study.

Omer Bagcilar, Deniz Alis, Ceren Alis, Mustafa Ege Seker, Mert Yergin, Ahmet Ustundag, Emil Hikmet, Alperen Tezcan, Gokhan Polat, Ahmet Tugrul Akkus and 7 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Omer Bagcilar *Radiology Department, Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey.
Deniz Alis *Radiology Department, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey. drdenizalis@gmail.com.
Ceren AlisNeurology Department, Istanbul Istinye State Hospital, Istanbul, Turkey.
Mustafa Ege SekerSchool of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Mert YerginArtificial Intelligence, and Information Technologies, Hevi AI Health, Istanbul, Turkey.
Ahmet UstundagRadiology Department, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Emil HikmetRadiology Department, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Alperen TezcanRadiology Department, School of Medicine, Erzurum Ataturk University, Istanbul, Turkey.
Gokhan PolatRadiology Department, School of Medicine, Erzurum Ataturk University, Istanbul, Turkey.
Ahmet Tugrul AkkusRadiology Department, School of Medicine, Erzurum Ataturk University, Istanbul, Turkey.
Fatih AlperRadiology Department, School of Medicine, Erzurum Ataturk University, Istanbul, Turkey.
Murat VeliogluRadiology Department, Istanbul Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Omer YildizRadiology Department, Istanbul Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Hakan Hatem SelcukRadiology Department, Istanbul Bakırköy Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Ilkay OksuzComputer Engineering Department, Istanbul Technical University, Istanbul, Turkey.
Osman KizilkilicRadiology Department, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Ercan KaraarslanRadiology Department, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of deep learning (DL) techniques for automated diagnosis of large vessel occlusion (LVO) and collateral scoring on computed tomography angiography (CTA) is gaining attention. In this study, a state-of-the-art self-configuring object detection network called nnDetection was used to detect LVO and assess collateralization on CTA scans using a multi-task 3D object detection approach. The model was trained on single-phase CTA scans of 2425 patients at five centers, and its performance was evaluated on an external test set of 345 patients from another center. Ground-truth labels for the presence of LVO and collateral scores were provided by three radiologists. The nnDetection model achieved a diagnostic accuracy of 98.26% (95% CI 96.25-99.36%) in identifying LVO, correctly classifying 339 out of 345 CTA scans in the external test set. The DL-based collateral scores had a kappa of 0.80, indicating good agreement with the consensus of the radiologists. These results demonstrate that the self-configuring 3D nnDetection model can accurately detect LVO on single-phase CTA scans and provide semi-quantitative collateral scores, offering a comprehensive approach for automated stroke diagnostics in patients with LVO.

Indexed as

Brain IschemiaStrokeCerebral AngiographyComputed Tomography AngiographyHumansMiddle Cerebral ArteryRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID37258516
PMCPMC10232534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.