Evidence map›Paper›PMID 37258281›Full record

ArticleJournal of movement disorders2023

Sex and Gender Influence Urinary Symptoms and Management in Multiple System Atrophy.

Elke Schipani Bailey, Sara J Hooshmand, Negin Badihian, Paola Sandroni, Eduardo E Benarroch, James H Bower, Phillip A Low, Wolfgang Singer, Elizabeth A Coon

Open access · diamondAbstract read
In one paragraph

Article in Journal of movement disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Multiple system atrophy related neurogenic bladder: mechanism and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  4. Sex-related differences in the clinical presentation of multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elke Schipani BaileyDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Sara J HooshmandDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Negin BadihianDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Paola SandroniDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Eduardo E BenarrochDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
James H BowerDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Phillip A LowDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Wolfgang SingerDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Elizabeth A CoonDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Synucleinopathies – Novel Targets in Early Diagnosis, Pathophysiology, and Therapeutic ApproachR01NS092625 · NINDS · MAYO CLINIC ROCHESTER · PI SINGER, WOLFGANG, VEMURI, PRASHANTHI · 2015 to 2025
$6.6M
NCATS NIH HHS UL1 TR002377NIH HHS R01 NS092625NIH HHS UL1 TR000135
6 · The paper itself

Abstract

objectiveMultiple system atrophy (MSA) is characterized by urinary dysfunction, yet the influence of sex and gender on urinary symptoms and treatment is unclear. We sought to characterize sex and gender differences in the symptomatology, evaluation, and management of urinary dysfunction in patients with MSA.

methodsPatients with MSA evaluated at our institution were reviewed and stratified by sex.

resultsWhile the prevalence of urinary symptoms was similar in male and female patients, incontinence was more common in females. Despite this, males and females underwent postvoid residual (PVR) measurement at similar rates. While catheterization rates were similar when PVR was measured, males were more than twice as likely to be catheterized than females in the absence of PVR measurement.

conclusionUrinary symptoms are common in MSA, but their presentation differs between males and females. The difference in catheterization rates may be driven by a gender disparity in referrals for PVR, which can guide treatment.

Indexed as

Gender differencesMultiple system atrophySex differencesUrinary failure

Identifiers

PMID37258281
PMCPMC10236018
OpenAlexW4377987193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.