ArticleClinical and experimental reproductive medicine2023
Human sperm parameter improvement associated with Ceratonia siliqua extract as a cryopreservation supplement after vitrification.
Article in Clinical and experimental reproductive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Protective Effect ofAntioxidants (Basel, Switzerland) · 2026Article
- Evaluation of the effect of mitoquinone on functional parameters, DNA structure, and genes expression related to the apoptotic and antioxidants of human sperm after freezing-thawing.Molecular biology reports · 2024Article
- Biological Activities ofInternational journal of molecular sciences · 2023Article
- Ceratonia Siliqua L: A Natural Compound with Big Impact on Male Reproductive System.American journal of men's healthReview
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveGiven the destructive effects of oxidative stress on sperm structure, this study was conducted to investigate the antioxidant effects of different concentrations of Ceratonia siliqua plant extract on human sperm parameters after the freezing-thawing process.
methodsA total of 20 normozoospermic samples were frozen. Each sample was divided into two control groups (fresh and cryopreservation) and three cryopreservation experimental groups (containing C. siliqua extract at concentrations of 20, 30, and 40 μg/mL in the freezing extender). Motility, intracellular levels of reactive oxygen species (ROS), plasma membrane integrity (PMI), mitochondrial membrane potential (MMP), viability, and acrosome reaction parameters were evaluated.
resultsStatistical analysis showed that the highest motility, viability, and PMI were associated with the 20 μg/mL concentration of C. siliqua extract. At all concentrations, intracellular ROS levels were significantly lower and the levels of MMP and the acrosome reaction were significantly higher than in the cryopreservation control group (p≤0.05).
conclusionC. siliqua extract supplements at concentrations of 20, 30, and 40 μg/mL improved sperm motility, viability, PMI, MMP, intracellular ROS, and the acrosome reaction.
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