Evidence map›Paper›PMID 37258043›Full record

ArticleRMD open2023

Genetic dissection of

Aya Kawasaki, Premita Ari Kusumawati, Yuka Kawamura, Yuya Kondo, Makio Kusaoi, Hirofumi Amano, Yasuyoshi Kusanagi, Kenji Itoh, Takashi Fujimoto, Naoto Tamura and 4 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Analysis of clinical features of lupus mesenteric vasculitis.Clinical and experimental medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Aya KawasakiMolecular and Genetic Epidemiology Laboratory, Institute of Medicine, University of Tsukuba, Tsukuba, Japan tsuchiya.nyk@gmail.com a-kawasaki@md.tsukuba.ac.jp.ORCID 0000-0002-5142-5610
Premita Ari KusumawatiMolecular and Genetic Epidemiology Laboratory, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Yuka KawamuraMolecular and Genetic Epidemiology Laboratory, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Yuya KondoDepartment of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Makio KusaoiDepartment of Internal Medicine and Rheumatology, Faculty of Medicine, Juntendo University, Tokyo, Japan.ORCID 0000-0003-0064-4765
Hirofumi AmanoDepartment of Internal Medicine and Rheumatology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Yasuyoshi KusanagiDivision of Hematology and Rheumatology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Japan.
Kenji ItohDivision of Hematology and Rheumatology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Japan.ORCID 0000-0002-4122-2983
Takashi FujimotoDepartment of General Medicine, Nara Medical University, Kashihara, Japan.
Naoto TamuraDepartment of Internal Medicine and Rheumatology, Faculty of Medicine, Juntendo University, Tokyo, Japan.ORCID 0000-0003-1729-2954
Hiroshi HashimotoSchool of Medicine, Juntendo University, Tokyo, Japan.
Isao MatsumotoDepartment of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Takayuki SumidaDepartment of Rheumatology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Naoyuki TsuchiyaMolecular and Genetic Epidemiology Laboratory, Institute of Medicine, University of Tsukuba, Tsukuba, Japan tsuchiya.nyk@gmail.com a-kawasaki@md.tsukuba.ac.jp.ORCID 0000-0002-6776-5580
University of Tsukuba · JPJuntendo University · JPNational Defense Medical College · JPNara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMajor histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations,

methodsAmong the XL9 variants, two (rs2105898 and rs9271593) previously associated variants in the European populations and two (rs9271375 and rs9271378) which showed a trend towards association in a Japanese Genome-Wide Association Study were selected. Associations of the XL9 variants and

resultsAmong the XL9 variants, associations of rs2105898T and rs9271593C were replicated in the Japanese population. However, these associations became no longer significant when conditioned on

conclusionIn the Japanese population,

Indexed as

Genome-Wide Association StudyLupus Erythematosus, SystemicEast Asian PeopleGenetic Predisposition to DiseaseHLA-DRB1 ChainsHumansHLA-DRB1*15:01 antigenHLA-DRB1 Chainsautoimmune diseasespolymorphism, geneticsystemic lupus erythematosus

Identifiers

PMID37258043
PMCPMC10255040
OpenAlexW4378907032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.