ArticleBMJ (Clinical research ed.)2023
Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.
Article in BMJ (Clinical research ed.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05229939 (Performances of Estimated Glomerular Filtration Rate Equations in Kidney Transplant Recipients), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Performances of Estimated Glomerular Filtration Rate Equations in Kidney Transplant Recipients
Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Artificial intelligence in chronic kidney disease: Early detection, risk prediction, and personalized treatment strategies.World journal of nephrology · 2026Review
- Prediction of Tacrolimus-Posaconazole Interactions in Renal Transplant Patients with Different CYP3A5 Genotypes, Based on Physiological Pharmacokinetic Models.Pharmaceutics · 2026Article
- Qualified prediction system for allograft failure in real world settings: extended validation study.BMJ medicine · 2026Article
- Combined Creatinine and Cystatin C Equations Improve Estimation of Glomerular Filtration Rate in Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Evaluation of race-free eGFR equations in individuals of different ethnicity.Blood pressure · 2025Article
- Microbiome-Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement.Clinical pharmacology and therapeutics · 2025Article
- Impact of Muscle Mass on the Performance of Creatinine-Based eGFR Equations and Mortality Risk Assessment After Kidney Transplantation.Journal of cachexia, sarcopenia and muscle · 2025Article
- New equation for estimating glomerular filtration rate in Vietnamese kidney transplant recipients.International urology and nephrology · 2025Article
- Sodium-Glucose Cotransporter-2 Inhibitor in Diabetic and Nondiabetic Renal Transplant Recipients.Kidney international reports · 2025Article
- The Patient and Treatment Characteristics of Kidney Transplant Recipients with a Clinically Relevant Jaffe/Enzymatic Serum Creatinine Difference.Journal of clinical medicine · 2025Article
- Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population.Kidney international reports · 2024Article
- Estimating glomerular filtration rate in kidney transplant recipients: considerations for selecting equations.Kidney international · 2024Article
- Immunosuppression and transplantation-related characteristics affect the difference between eGFR equations based on creatinine compared to cystatin C in kidney transplant recipients.Clinical kidney journal · 2024Article
- Associations between Kidney Disease Progression and Metabolomic Profiling in Stable Kidney Transplant Recipients-A 3 Year Follow-Up Prospective Study.Journal of clinical medicine · 2024Article
- Race and ethnicity in physiological research: When socio-political constructs and biology collide.Experimental physiology · 2024Article
- Do We Need a New Creatinine-Based Estimated GFR Equation for Kidney Transplant Recipients?American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024Article
- Living donors kidney transplantation and oxidative stress: Nitric oxide as a predictive marker of graft function.PloS one · 2024Article
- Proceedings of the 2024 Transplant AI Symposium.Frontiers in transplantation · 2024Article
- Performance of the race-free CKD-EPI creatinine-based eGFR equation in a Danish cohort with measured GFR.Clinical kidney journal · 2023Article
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Authors and funding
36 authors at 17 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the performance of a newly developed race-free kidney recipient specific glomerular filtration rate (GFR) equation with the three current main equations for measuring GFR in kidney transplant recipients.
designDevelopment and validation study
setting17 cohorts in Europe, the United States, and Australia (14 transplant centres, three clinical trials).
participants15 489 adults (3622 in development cohort (Necker, Saint Louis, and Toulouse hospitals, France), 11 867 in multiple external validation cohorts) who received kidney transplants between 1 January 2000 and 1 January 2021.
main outcome measureThe main outcome measure was GFR, measured according to local practice. Performance of the GFR equations was assessed using P
resultsThe study included 15 489 participants, with 50 464 mGFR and eGFR values. The mean GFR was 53.18 mL/min/1.73m
conclusionA new race-free kidney recipient specific GFR equation was developed and validated using multiple, large, international cohorts of kidney transplant recipients. The equation showed high accuracy and outperformed the race-free CKD-EPI 2021 equation that was developed in individuals with native kidneys.
trial registrationClinicalTrials.gov NCT05229939.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.