Evidence map›Paper›PMID 37257165›Full record

ArticleJournal of the American Chemical Society2023

Cascaded, Feedback-Driven, and Spatially Localized Emergence of Constitutional Dynamic Networks Driven by Enzyme-Free Catalytic DNA Circuits.

Zhixin Zhou, Nina Lin, Yu Ouyang, Songqin Liu, Yuanjian Zhang, Itamar Willner

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhixin ZhouSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Nina LinSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Yu OuyangInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0002-2418-281X
Songqin LiuSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.ORCID 0000-0002-4686-5291
Yuanjian ZhangSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.ORCID 0000-0003-2932-4159
Itamar WillnerInstitute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0001-9710-9077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The enzyme-free catalytic hairpin assembly (CHA) process is introduced as a functional reaction module for guided, high-throughput, emergence, and evolution of constitutional dynamic networks, CDNs, from a set of nucleic acids. The process is applied to assemble networks of variable complexities, functionalities, and spatial confinement, and the systems provide possible mechanistic pathways for the evolution of dynamic networks under prebiotic conditions. Subjecting a set of four or six structurally engineered hairpins to a promoter P

Indexed as

Biosensing TechniquesDNA, CatalyticNanostructuresCatalysisDNAFeedbackDNADNA, Catalytic

Identifiers

PMID37257165
PMCPMC10273234

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.