Evidence map›Paper›PMID 37256604›Full record

ArticleEuropean thyroid journal2023

Trends in radioactive iodine treatment after total thyroidectomy in Italy, 2001-2018.

Luigino Dal Maso, Daniela Pierannunzio, Silvia Francisci, Angela De Paoli, Federica Toffolutti, Salvatore Vaccarella, Silvia Franceschi, Rossella Elisei, Ugo Fedeli

Open access · diamondAbstract read
In one paragraph

Article in European thyroid journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luigino Dal MasoCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.ORCID 0000-0001-6163-200X
Daniela PierannunzioNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Silvia FrancisciNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Angela De PaoliEpidemiological Department, Azienda Zero, Padova, Italy.
Federica ToffoluttiCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Salvatore VaccarellaSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
Silvia FranceschiCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Rossella EliseiDepartment of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, Pisa, Italy.
Ugo FedeliEpidemiological Department, Azienda Zero, Padova, Italy.
Centro di Riferimento Oncologico · ITIstituto Superiore di Sanità · ITAzienda Ospedaliera Universitaria Pisana · ITCentre international de recherche sur le cancer · FR

Funding

World Health Organization 001
6 · The paper itself

Abstract

Objective: A decrease in the use of radioactive iodine (RAI) treatment for thyroid cancer has been described in the last decade in the US following subsequent updates of the American Thyroid Association guidelines. By contrast, population-based data from European countries are lacking. The study aims to assess the frequency and long-term trends in the use of RAI in Italy. Methods: From the Italian national hospital discharge database, the proportion of RAI treatment after total thyroidectomy with thyroid cancer diagnosis has been assessed by sex and age class during 2001-2018. Results: Throughout the whole study period, RAI was performed after 58% of 149,419 total thyroidectomies. The use of RAI was higher for men and younger patients; it peaked in 2007 (64% in women and 68% in men) and declined thereafter (2018: 46% in women and 53% in men), with a similar pattern observed across all ages and areas. Conclusion: National data show that in Italy trends in RAI treatment paraleled those observed in the US. Further monitoring of the use of RAI is warranted in Italy, as elsewhere, to assess the impact of international guidelines on real-life clinical management of thyroid cancer.

Indexed as

ThyroidectomyThyroid NeoplasmsFemaleHumansIodine RadioisotopesItalyMaleIodine RadioisotopesItalyradioactive iodine (RAI)thyroidectomiesthyroid surgerytime trends

Identifiers

PMID37256604
PMCPMC10388682
OpenAlexW4378783609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.