ArticleUrologie (Heidelberg, Germany)2023
[Long-term evaluation of low-dose-rate (LDR) brachytherapy in localized prostate cancer].
Article in Urologie (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors at 3 institutions in 1 country.
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Abstract
BACKGROUND AND
objectivesAs a result of technical innovation, i.e., improvement of seed quality, implantation method, and dose calculation, it has been possible to continuously improve oncological results in the treatment of localized prostate cancer with low-dose-rate brachytherapy (LDR-BT). Randomized controlled trials have shown that there is no significant difference in oncological control between the use of radical prostatectomy and LDR-BT in patients with low-risk prostate cancer. The objective of this study was to investigate the oncological efficacy of LDR-BT. MATERIALS AND
methodsA retrospective multicenter analysis was conducted on 618 patients treated with LDR-BT as monotherapy, who received a dose of 145 Gy. We used iodine
resultsMedian follow-up was 52 months (range 3-180 months). The bRFS across all risk groups was 87.87%. Oncological efficacy was significantly higher in patients with a Gleason score of 6 and 7a (p-value < 0.0001); however, there was no significant difference in bRFS between these two groups. Bilateral tumor infiltration or prostate volume had no significant influence on bRFS.
conclusionOur results show no difference in bRFS between Gleason score 6 and 7a.
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