ReviewWorld journal of microbiology & biotechnology2023
Recent advances in the biological activities of microbial exopolysaccharides.
Review in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Fermentation-A Potential Game Changer in the Development of Plant-Based Cream Cheese Alternatives.Foods (Basel, Switzerland) · 2026Review
- Effects of Aspen Wood Torrefaction Condensate Addition onMarine drugs · 2026Article
- Water-soluble sulfated exopolysaccharide from Cytobacillus oceanisediminis: Its production, characterization and biological activities.Folia microbiologica · 2026Article
- The biostimulant role of microbial exopolysaccharides: mechanisms and agricultural applications.World journal of microbiology & biotechnology · 2026Review
- Statistical optimization of exopolysaccharides by indigenously isolated Lactobacillus strain under submerged fermentation.World journal of microbiology & biotechnology · 2026Article
- Enhanced Barley Growth in Petroleum-Contaminated Soil Mediated by Xanthan-like Exopolysaccharide ofMicroorganisms · 2026Article
- Rhizobacteria Exopolysaccharide: A Boon in Reclaiming Soil Fertility, Augmenting Plant Growth and Plant Stress Resilience.Environmental microbiology reports · 2026Review
- Genomic and proteomic characterization of a newly isolatedMicrobiology spectrum · 2026Article
- Exopolysaccharides from lactic acid bacteria: functional ingredients with biotechnological potential - a critical review.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Review
- Hypoglycemic and Antioxidant Activities of Exopolysaccharides Produced by Lactic Acid Bacteria: A Systematic Review.Preventive nutrition and food science · 2025Review
- Review
- Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.Gut microbes · 2025Review
- Gut-Protective and Multifunctional Exopolysaccharide fromNutrients · 2025Article
- Revealing the therapeutic potential of bioactive exopolysaccharide (EPSS10) derived from Streptomyces sp. MAE.BMC microbiology · 2025Article
- Functional and genomic evaluation of novel exopolysaccharide produced by marine Pediococcus pentosaceus E3 with antidiabetic, anticancer, and anti-inflammatory potentials.BMC microbiology · 2025Article
- Prophylactic and therapeutic effects of Limosilactobacillus reuteri E on 5-fluorouracil-induced intestinal mucositis in Caco-2 cells.Folia microbiologica · 2025Article
- Mannan-Containing Polymers from Hadal BacteriumMarine drugs · 2025Article
- A Study on the Extraction, Fermentation Condition Optimization, and Antioxidant Activity Assessment of Polysaccharides Derived fromFoods (Basel, Switzerland) · 2025Article
- Antimicrobial and prebiotic properties ofIranian journal of microbiology · 2025Article
- The Enzyme Glucose-1-Phosphate Thymidylyltransferase RmlA Plays a Crucial Role in the Pathogenesis of Pectobacterium actinidiae GX1.Molecular plant pathology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial exopolysaccharides (EPSs) are valuable extracellular macromolecules secreted as capsules or slime layers. Various microorganisms, including bacteria, yeasts, fungi, and algae have been studied for their ability to produce EPSs. Microbial EPSs exist as homopolysaccharides or heteropolysaccharides with various properties such as different monosaccharide compositions, structural conformation, molecular weight, and functional groups. They are cost-effective alternatives to plant and animal-derived polysaccharides because the microbial cells produced them in large quantities by biotechnological processes using low-cost substrates such as industrial wastes in a short time. Microbial EPSs are safe, biodegradable, and compatible polymers. They have extensive bioactivities, including antibacterial, antifungal, antiviral, antioxidant, antitumor, antidiabetic, antiulcer, anticoagulant, antiaging, immunomodulatory, wound healing, and cholesterol-lowering activities. Microbial EPSs owing to biological activities, special biochemical structures, and attractive physicochemical properties find plenty of potential applications in various industries. The enhancement of the production of EPSs and improving their properties can be provided by genetic engineering methods. The current review aims to provide a comprehensive examination of the therapeutic activities of microbial EPSs in infectious diseases and metabolic disorders, with a focus on the mechanisms involved. Also, the effect of the physicochemical characteristics of EPSs on these bioactivities was discussed to reveal the structure-activity relationship.
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