Evidence map›Paper›PMID 37256254›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2023

Medications for Alcohol Use Disorder and Retention in Care in Medicaid-Enrolled Youth, 2014-2019.

Joel J Earlywine, Sarah M Bagley, Jonathan Rodean, Bonnie T Zima, Nicholas Chadi, Douglas L Leslie, Scott E Hadland

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Joel J EarlywineMathematica, Seattle, Washington; Department of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts.
Sarah M BagleyGrayken Center for Addiction and Department of Pediatrics, Boston Medical Center, Boston, Massachusetts; Division of General Pediatrics, Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Jonathan RodeanChildren's Hospital Association, Lenexa, Kansas.
Bonnie T ZimaUCLA-Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California.
Nicholas ChadiDivision of Adolescent Medicine, Department of Pediatrics, Sainte-Justine University Hospital Centre, University of Montreal, Montreal, Quebec, Canada.
Douglas L LeslieDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania.
Scott E HadlandGrayken Center for Addiction and Department of Pediatrics, Boston Medical Center, Boston, Massachusetts; Division of General Pediatrics, Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts; Division of Adolescent and Young Adult Medicine, Mass General for Children, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts. Electronic address: shadland@mgh.harvard.edu.
Boston University · USCentre Hospitalier Universitaire Sainte-Justine · CAChildren's Hospital Association · USPennsylvania State University · USUniversity of California, Los Angeles · US

Funding

The Cascade of Care for Medicaid-Enrolled Youth with Opioid Use DisorderR01DA057566 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Scott Evan Hadland · 2022 to 2026
$2.9M
Collaborative Care Office-Based Opioid Treatment for Adolescents and Young AdultsK23DA045085 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HADLAND, SCOTT EVAN · 2018 to 2022
$1.1M
A Behavioral Intervention to Engage Emerging Adults in Addiction Treatment after a Non-fatal Opioid OverdoseK23DA044324 · NIDA · BOSTON MEDICAL CENTER · PI BAGLEY, SARAH M · 2017 to 2021
$938k
NIDA NIH HHS K23 DA044324NIDA NIH HHS K23 DA045085NIDA NIH HHS L40 DA042434NIDA NIH HHS R01 DA057566
6 · The paper itself

Abstract

purposeAlcohol use disorder (AUD) is a pediatric-onset condition needing timely, effective treatment. Medications for AUD are part of nationally recommended treatments for youth. This study measured receipt of medications and behavioral health services for AUD and subsequent retention in care.

methodsThis retrospective cohort study used claims data from > 4.7 million publicly insured youth aged 13-22 years in 15 states from 2014-2019. Timely treatment was defined as receipt of medication (naltrexone, acamprosate, or disulfiram) and/or behavioral health services within 30 days of incident AUD diagnosis. Associations of age and other characteristics with timely treatment were identified using modified Poisson regression. Retention in care (i.e., no period ≥ 60 days without claims) was studied using Cox regression.

resultsAmong 14,194 youth with AUD, 10,851 (76.4%) received timely treatment. Only 2.1% of youth received medication (alone or in combination); nearly all (97.9%) received behavioral health services only. Older (aged 16-17 years) and younger adolescents (aged 13-15 years) were 0.13 (95% confidence interval [CI], 0.07-0.26) and 0.24 (95% CI, 0.11-0.51) times as likely, respectively, to receive medications than young adults aged ≥ 21 years. Median retention in care for youth receiving medications was 119 days (interquartile range, 54-321) compared with 108 days (interquartile range, 43-243) for behavioral health services alone (p = .126). Young adults aged ≥ 18 years were 1.12 (95% CI, 1.06-1.18) times as likely to discontinue treatment compared with adolescents aged < 18 years. DISCUSSION: This study found that more than seven in 10 youth received AUD treatment but only two in 100 received medications. Future studies should further characterize the effectiveness of medications and determine whether low rates of receipt represent underuse.

Indexed as

AlcoholismRetention in CareAdolescentChildHumansMedicaidNaltrexoneRetrospective StudiesUnited StatesYoung AdultNaltrexoneAdolescentAlcohol use disorderRetention in careSubstance use disordersYoung adult

Identifiers

PMID37256254
PMCPMC10593088
OpenAlexW4378675540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.