Evidence map›Paper›PMID 37256117›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Activation effects on the physical characteristics of T lymphocytes.

Richard E Waugh, Elena Lomakina, Andrea Amitrano, Minsoo Kim

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Richard E WaughDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Elena LomakinaDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, United States.
Andrea AmitranoDepartment of Pathology, University of Rochester Medical Center, Rochester, NY, United States.
Minsoo KimDepartment of Microbiology and Immunology, David H. Smith Center for Vaccine Biology and Immunology, University of Rochester, Rochester, NY, United States.

Funding

T cell migration and cardiovascular toxicity in immunotherapyR01AI147362 · NIAID · UNIVERSITY OF ROCHESTER · PI Minsoo Kim, Richard E Waugh · 2019 to 2026
$4.2M
NIAID NIH HHS R01 AI147362
6 · The paper itself

Abstract

The deformability of leukocytes is relevant to a wide array of physiological and pathophysiological behaviors. The goal of this study is to provide a detailed, quantitative characterization of the mechanical properties of T cells and how those properties change with activation. We tested T cells and CD8

Indexed as

cell activationcell therapeuticsmechanicsmicropipetteT cells

Identifiers

PMID37256117
PMCPMC10225623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.