Evidence map›Paper›PMID 37256116›Full record

ReviewFrontiers in bioengineering and biotechnology2023

Graphene-based cardiac sensors and actuators.

Alex Savchenko, Dmitry Kireev, Rose T Yin, Igor R Efimov, Elena Molokanova

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Atomically thin bioelectronics.Nature reviews. Materials · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alex SavchenkoNanotools Bioscience, La Jolla, CA, United States.
Dmitry KireevMicroelectronics Research Center, Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, United States.
Rose T YinDepartment of Biomedical Engineering, The George Washington University, Washington, DC, United States.
Igor R EfimovDepartment of Biomedical Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Chicago, IL, United States.
Elena MolokanovaNanotools Bioscience, La Jolla, CA, United States.

Funding

High-Definition Conformal Electronics for VT/VFR01HL141470 · NHLBI · NORTHWESTERN UNIVERSITY · PI EFIMOV, IGOR R · 2019 to 2022
$2.5M
Graphene optoelectronic biointerfaces for enabling optical cardiac pacemakingR21HL152324 · NHLBI · NORTHWESTERN UNIVERSITY · PI EFIMOV, IGOR R, LU, LUYAO · 2020 to 2021
$440k
Non-genetic optical stimulation platform for the next-generation neuroscience drug discovery assaysR43MH124563 · NIMH · NANOTOOLS BIOSCIENCE · PI SAVTCHENKO, ALEX · 2021 to 2021
$350k
LightKick: Novel bioengineering system for activity-dependent acceleration of functional maturation of human stem cell-derived cardiomyocytesR43TR003252 · NCATS · NANOTOOLS BIOSCIENCE · PI SAVTCHENKO, ALEX · 2020 to 2020
$325k
Novel nanotechnology-based optical stimulation platform for predictive cardiotoxicity assessmentR43TR001911 · NCATS · NANOTOOLS BIOSCIENCE · PI SAVTCHENKO, ALEX · 2017 to 2017
$325k
FDA HHS U01 FD006676NCATS NIH HHS R43 TR001911NCATS NIH HHS R43 TR003252NHLBI NIH HHS R01 HL141470NHLBI NIH HHS R21 HL152324NIMH NIH HHS R43 MH124563
6 · The paper itself

Abstract

Graphene, a 2D carbon allotrope, is revolutionizing many biomedical applications due to its unique mechanical, electrical, thermal, and optical properties. When bioengineers realized that these properties could dramatically enhance the performance of cardiac sensors and actuators and may offer fundamentally novel technological capabilities, the field exploded with numerous studies developing new graphene-based systems and testing their limits. Here we will review the link between specific properties of graphene and mechanisms of action of cardiac sensors and actuators, analyze the performance of these systems from inaugural studies to the present, and offer future perspectives.

Indexed as

cardiacgraphenegraphene biosensorsgraphene electrodesgraphene field electric transistorsgraphene-mediated optical stimulationoptoelectronicspacemaker

Identifiers

PMID37256116
PMCPMC10225741

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.