Evidence map›Paper›PMID 37255928›Full record

ReviewOxford open immunology2023

Autoimmunity in Long Covid and POTS.

Fatema-Zahra El-Rhermoul, Artur Fedorowski, Philip Eardley, Patricia Taraborrelli, Dimitrios Panagopoulos, Richard Sutton, Phang Boon Lim, Melanie Dani

Open access · goldAbstract readReview
In one paragraph

Review in Oxford open immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Elevated blood viscosity is associated with dysautonomia in long COVID symptoms.American heart journal plus : cardiology research and practice · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Kidney involvement and anemia in COVID-19 infection.World journal of nephrology · 2025
    Review
  10. A pain from the nose to the head: neurological commitment during long COVID.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  16. Prevalence and associations of insomnia after COVID-19 infection.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Fatema-Zahra El-RhermoulDepartment of Allergy and Clinical Immunology, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Artur FedorowskiDepartment of Cardiology, Karolinska University Hospital and Karolinska Institute, Stockholm 171 77, Sweden.
Philip EardleyImperial Syncope Unit, Imperial College Healthcare NHS Trust, London W12 0HS, UK.
Patricia TaraborrelliImperial Syncope Unit, Imperial College Healthcare NHS Trust, London W12 0HS, UK.
Dimitrios PanagopoulosImperial Syncope Unit, Imperial College Healthcare NHS Trust, London W12 0HS, UK.
Richard SuttonNational Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
Phang Boon LimImperial Syncope Unit, Imperial College Healthcare NHS Trust, London W12 0HS, UK.
Melanie DaniImperial Syncope Unit, Imperial College Healthcare NHS Trust, London W12 0HS, UK.ORCID https://orcid.org/0000-0002-5113-7248
Imperial College Healthcare NHS Trust · GBGuy's and St Thomas' NHS Foundation Trust · GBKarolinska University Hospital · SELung Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthostatic intolerance and other autonomic dysfunction syndromes are emerging as distinct symptom clusters in Long Covid. Often accompanying these are common, multi-system constitutional features such as fatigue, malaise and skin rashes which can signify generalized immune dysregulation. At the same time, multiple autoantibodies are identified in both Covid-related autonomic disorders and non-Covid autonomic disorders, implying a possible underlying autoimmune pathology. The lack of specificity of these findings precludes direct interpretations of cause and association, but their prevalence with its supporting evidence is compelling.

Indexed as

autoantibodyautoimmuneautoimmunityLong CovidPOTS

Identifiers

PMID37255928
PMCPMC10224806
OpenAlexW4323438485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.