Evidence map›Paper›PMID 37255770›Full record

ArticleJournal of diabetes and metabolic disorders2023

Dose-response relationship of photobiomodulation therapy and oxidative stress markers in healing dynamics of diabetic neuropathic ulcers in Wistar rats.

Gagana Karkada, G Arun Maiya, Praveen Arany, Mohandas Rao Kg, Shalini Adiga, Shobha U Kamath

Open access · hybridAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gagana KarkadaCentre for Diabetic Foot Care and Research, Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, 576 104 Manipal, Karnataka India.ORCID 0000-0003-1977-2716
G Arun MaiyaDepartment of Physiotherapy, Chief- Centre for Diabetic Foot Care and Research, Manipal College of Health Professions, Manipal Academy of Higher Education, 576 104 Manipal, Karnataka India.ORCID 0000-0001-7573-0137
Praveen AranyDepartment of Oral Biology, School of Dental Medicine, Engineering & Applied Sciences, University at Buffalo, 3435 Main Street, B36A, Foster Hall- Buffalo, NY14214-8031 New York, USA.ORCID 0000-0002-6116-2340
Mohandas Rao KgDepartment of Anatomy, Melaka Manipal Medical College- Manipal, Manipal Academy of Higher Education, 576104 Manipal, Karnataka India.ORCID 0000-0001-5832-0718
Shalini AdigaDepartment of Pharmacology, Kasturba Medical College, Manipal Academy of Higher Education, 576 104 Manipal, Karnataka India.ORCID 0000-0002-3369-194X
Shobha U KamathDepartment of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, 576104 Manipal, Karnataka India.ORCID 0000-0002-9896-0872
Manipal Academy of Higher Education · INUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Diabetic foot ulcers are reported to be the most expensive complications of diabetes, with high morbidity and mortality rates. If the necessary care is not provided for the wound to heal, the individual may end up amputating the affected feet. Photobiomodulation therapy is a promising non-pharmacological treatment option for wound healing. The objective of the present study is to establish a dose-response relationship between photobiomodulation therapy and oxidative stress markers in the healing dynamics of diabetic neuropathic ulcers in Wistar rats. Methodology: Diabetic neuropathy was induced in 126 Albino Wistar rats. An excisional wound of an area of 2cm Results: In the experimental group, animals treated with photobiomodulation therapy at doses of 4, 6, and 8 J/cm Conclusion: Photobiomodulation therapy of dosages 4, 6, and 8 J/cm Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-022-01157-2.

Indexed as

Diabetic neuropathic ulcerDose-responseOxidative stress markersPhotobiomodulation therapyWound healing

Identifiers

PMID37255770
PMCPMC10225440
OpenAlexW4312193794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.