ReviewFrontiers in public health2023
The risk profile of electronic nicotine delivery systems, compared to traditional cigarettes, on oral disease: a review.
Review in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Tobacco Smoking and Smoke-Free Products as Risk Factors for Dental Implants: A Systematic Review.Clinical oral implants research · 2026Pooled it
- The impact of electronic and conventional cigarettes on periodontal health-a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- Longitudinal comparison of peri-implant clinical and radiographic parameters between e-cigarette users and conventional cigarette smokers.BMC oral health · 2026Article
- Impact of Electronic Nicotine Delivery Systems on Oral Mucosa: A Cytopathological and Molecular Study.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
- Governing E-cigarettes in China: regulatory challenges and strategies for adolescent protection in the post-flavor ban era.Frontiers in public health · 2026Article
- Diverse Impact of E-Cigarette Aerosols on Oxidative Stress and Inflammation in Lung Alveolar Epithelial Cells (A549).International journal of molecular sciences · 2025Article
- Impact of E-Cigarette Vapor and Cigarette Smoke on Brain Expression of ABCB1 and ABCG2 Efflux Transporters.Neurochemical research · 2025Article
- Electronic Cigarette Use (Vaping) Among Adolescents: A Narrative Review of an Emerging Public Health Epidemic.Cureus · 2025Review
- Halitosis among users of electronic nicotine delivery systems in a multi-center cross-sectional study.Scientific reports · 2025Article
- Decoding different oxidative stress pathways in periodontitis: a comparative review of mechanisms of traditional tobacco smoke and electronic smoke aerosol.Archives of toxicology · 2025Review
- EBM BLS: Varenicline Improves Electronic Cigarette Quit Success Rate.Journal of general internal medicine · 2025Article
- Comparing self-rated health among exclusive e-cigarette users and traditional cigarette smokers: an analysis of the Health Survey for England 2019.Internal and emergency medicine · 2025Article
- Influence of electronic cigarette vapour on theBiomaterial investigations in dentistry · 2025Article
- Factors influencing sialorrhea in orally intubated patients: a lasso and logistic regression analysis.Frontiers in medicine · 2025Article
- Oral health risks in adults who use electronic nicotine delivery systems and oral nicotine pouches: a critical review of the literature and qualitative synthesis of the available evidence.Harm reduction journal · 2024Review
- Stimulus mediation, specificity and impact of menthol in rats trained to discriminate puffs of nicotine e-cigarette aerosol from nicotine-free aerosol.Psychopharmacology · 2024Article
- Sensitivity of Mouse Lung Nuclear Receptors to Electronic Cigarette Aerosols and Influence of Sex Differences: A Pilot Study.International journal of environmental research and public health · 2024Article
- Effects of e-cigarette smoking on periodontal health: A scoping review.PLOS global public health · 2024Article
- Characterizing Tobacco Usage in Otolaryngology Patients to Target Smoking Cessation Efforts.Tobacco use insights · 2024Article
- [Association of cigarette consumption, nicotine derivatives and cannabis with periodontal disease. A review].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of electronic nicotine delivery systems (ENDS) has exploded, especially among teenagers and new smokers, amid widespread awareness of the dangers of traditional tobacco and restrictions on smoking. However, the risk effects of ENDS on physical health, especially oral health, are still ambiguous. The purpose of this study was to review the available evidence on risks of ENDS on oral health, and compares the differences between ENDS and traditional cigarettes. For heavy smokers, transferring the addiction of tobacco to ENDS can be less harmful to periodontal condition and physical health but is not completely without risk. The components of ENDS vapor have cytotoxic, genotoxic, and carcinogenic properties, and its usage may be associated with a wide range of oral health sequelae. The chemicals in ENDS increase the susceptibility to tooth decay, increase the risk of periodontal disease, peri-implant, and oral mucosal lesions. Nicotine aerosols from ENDS can be a potential risk factor for oral cancer due to the presence of carcinogenic components. Compared to smoking traditional cigarettes, the harm associated with ENDS use may be underestimated due to the reduced ability to control vaping behavior, ease of ENDS access, fewer vaping area restrictions, and better taste. Currently, the available evidence suggests that ENDS may be a safer alternative to traditional tobacco products. Though most oral symptoms experienced by ENDS users are relatively mild and temporary compared to traditional cigarettes, the dangers of ENDS still exist. However, further research with longer follow-up periods is required to establish the long-term safety of ENDS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.