Evidence map›Paper›PMID 37255617›Full record

ArticleClinical case reports2023

Use of the osmolal gap in diagnosing mixed physiology hyponatremia in a child with B-cell acute lymphoblastic leukemia.

Jonathan M Gabbay, Andrew E Place, Maya Ilowite, Jia Zhu

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Integrating Physiology Into Hyponatremia Algorithms: Moving Beyond Volume Status.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan M GabbayDepartment of Medicine Boston Children's Hospital Boston Massachusetts USA.ORCID https://orcid.org/0000-0003-2763-986X
Andrew E PlaceHarvard Medical School Boston Massachusetts USA.
Maya IlowiteHarvard Medical School Boston Massachusetts USA.
Jia ZhuHarvard Medical School Boston Massachusetts USA.

Funding

Dissecting PCOS Physiology by Defining Phenotypes Associated with PCOS Genetic Risk Factors in Men and ChildrenF32HD103317 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ZHU, JIA · 2021 to 2022
$158k
NICHD NIH HHS F32 HD103317
6 · The paper itself

Abstract

Hyponatremia is common among children undergoing treatment for hematologic malignancies and may be attributed to multiple underlying causes. In cases of hyponatremia due to mixed physiology, the osmolal gap, can identify pseudohyponatremia that may be masked by other causes.

Indexed as

hypertriglyceridemiahyponatremiainappropriate ADH syndromeprecursor cell lymphoblastic leukemia‐lymphoma

Identifiers

PMID37255617
PMCPMC10225615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.