Evidence map›Paper›PMID 37255571›Full record

ReviewFrontiers in pediatrics2023

Leveraging the placenta to advance neonatal care.

Karen K Mestan, Sandra L Leibel, Eniko Sajti, Betty Pham, Samantha Hietalati, Louise Laurent, Mana Parast

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Stem/Progenitor Cells and Related Therapy in Bronchopulmonary Dysplasia.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Karen K MestanDepartment of Pediatrics/Division of Neonatology, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Sandra L LeibelDepartment of Pediatrics/Division of Neonatology, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Eniko SajtiDepartment of Pediatrics/Division of Neonatology, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Betty PhamDepartment of Pediatrics/Division of Neonatology, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Samantha HietalatiDepartment of Pediatrics/Division of Neonatology, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Louise LaurentDepartment of Obstetrics, Gynecology and Reproductive Sciences/Division of Maternal Fetal Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Mana ParastSanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
Rady Children's Hospital-San Diego · USUniversity of California San Diego · USSanford Consortium for Regenerative Medicine · US

Funding

The Role of Placental Maternal Vascular Underperfusion in Neonatal Pulmonary HypertensionR01HL139798 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MESTAN, KAREN K · 2018 to 2022
$2.5M
NHLBI NIH HHS R01 HL139798
6 · The paper itself

Abstract

The impact of placental dysfunction and placental injury on the fetus and newborn infant has become a topic of growing interest in neonatal disease research. However, the use of placental pathology in directing or influencing neonatal clinical management continues to be limited for a wide range of reasons, some of which are historical and thus easily overcome today. In this review, we summarize the most recent literature linking placental function to neonatal outcomes, focusing on clinical placental pathology findings and the most common neonatal diagnoses that have been associated with placental dysfunction. We discuss how recent technological advances in neonatal and perinatal medicine may allow us to make a paradigm shift, in which valuable information provided by the placenta could be used to guide neonatal management more effectively, and to ultimately enhance neonatal care in order to improve our patient outcomes. We propose new avenues of clinical management in which the placenta could serve as a diagnostic tool toward more personalized neonatal intensive care unit management.

Indexed as

bronchopulmonary dysplasia (BPD)chorioamnionitisneonatal intensive care unit (NICU)neonatal outcomeplacental pathologypreeclampsiaprematurity and low birth weight

Identifiers

PMID37255571
PMCPMC10225648
OpenAlexW4378783079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.