Evidence map›Paper›PMID 37255569›Full record

ArticleCerebral cortex communications2023

Multivariate associations between dopamine receptor availability and risky investment decision-making across adulthood.

Mikella A Green, Jennifer L Crawford, Camelia M Kuhnen, Gregory R Samanez-Larkin, Kendra L Seaman

Open access · hybridAbstract read
In one paragraph

Article in Cerebral cortex communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mikella A GreenDepartment of Psychology & Neuroscience, 417 Chapel Dr, Durham, NC 27708, Center for Cognitive Neuroscience, Duke University, 308 Research Drive, Durham, NC 27708.
Jennifer L CrawfordDepartment of Psychology, Brandeis University, 415 South Street, Waltham, MA 02453.
Camelia M KuhnenUNC Kenan-Flagler Business School, 300 Kenan Center Drive, Chapel Hill, NC 27599, National Bureau of Economic Research, 1050 Massachusetts Avenue, Cambridge, MA 02138.
Gregory R Samanez-LarkinDepartment of Psychology & Neuroscience, 417 Chapel Dr, Durham, NC 27708, Center for Cognitive Neuroscience, Duke University, 308 Research Drive, Durham, NC 27708.ORCID https://orcid.org/0000-0001-7846-3804
Kendra L SeamanDepartment of Psychology, University of Texas at Dallas, 800 W Campbell Road, Richardson, TX 75080-3021, Center for Vital Longevity, University of Texas at Dallas, 1600 Viceroy Drive, Suite 800, Dallas, TX 75235.ORCID https://orcid.org/0000-0003-3008-923X
Duke University · USBrandeis University · USNational Bureau of Economic Research · USThe University of Texas at Dallas · US

Funding

BEHAVIOR AND PHYSIOLOGY IN AGINGT32AG000029 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 1985 to 2026
$9.3M
NIA NIH HHS T32 AG000029
6 · The paper itself

Abstract

Enhancing dopamine increases financial risk taking across adulthood but it is unclear whether baseline individual differences in dopamine function are related to risky financial decisions. Here, thirty-five healthy adults completed an incentive-compatible risky investment decision task and a PET scan at rest using [11C]FLB457 to assess dopamine D2-like receptor availability. Participants made choices between a safe asset (bond) and a risky asset (stock) with either an expected value less than the bond ("bad stock") or expected value greater than the bond ("good stock"). Five measures of behavior (choice inflexibility, risk seeking, suboptimal investment) and beliefs (absolute error, optimism) were computed and D2-like binding potential was extracted from four brain regions of interest (midbrain, amygdala, anterior cingulate, insula). We used canonical correlation analysis to evaluate multivariate associations between decision-making and dopamine function controlling for age. Decomposition of the first dimension (

Indexed as

canonical correlation analysisdecision-makingdopaminefinancial risk takingPET

Identifiers

PMID37255569
PMCPMC10225308
OpenAlexW4376613429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.