Evidence map›Paper›PMID 37255485›Full record

ArticleChembiochem : a European journal of chemical biology2023

Systematic Structural Tuning Yields Hydrazonyl Sultones for Faster Bioorthogonal Protein Modification.

Ming Fang, Gangam Srikanth Kumar, Qing Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Protein Modification via Bioorthogonal HS-BCN Ligation.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ming FangDepartment of Chemistry, State University of New York at Buffalo, Buffalo, NY, 14260-3000, USA.ORCID 0000-0002-1566-4825
Gangam Srikanth KumarDepartment of Chemistry, State University of New York at Buffalo, Buffalo, NY, 14260-3000, USA.ORCID 0000-0002-6052-9913
Qing LinDepartment of Chemistry, State University of New York at Buffalo, Buffalo, NY, 14260-3000, USA.ORCID 0000-0002-9196-5718

Funding

Development and Applications of Bioorthogonal Chemistry: Equipment SupplementR35GM130307 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Qing Lin · 2019 to 2026
$3.6M
NIGMS NIH HHS R35 GM130307NIH HHS R35GM130307
6 · The paper itself

Abstract

We report the synthesis of a series of hydrazonyl sultones (HS) containing an ortho-CF

Indexed as

NaphthalenesulfonatesProteinsNaphthalenesulfonatesnaphthosultoneProteinsBioorthogonal reactionHydrazonyl sultoneNanobodyNitrile imineTautomerization

Identifiers

PMID37255485
PMCPMC10424513

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.