Evidence map›Paper›PMID 37255468›Full record

ArticleInfection and immunity2023

Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection.

Brandon M Wills, Preeti Garai, Molly O Riegert, Felix T Sanchez, Adam M Pickrum, Dara W Frank, Kenneth L Brockman

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Establishment of a chinchilla model ofMicrobiology spectrum · 2026
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  4. mSphere · 2026
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  5. Establishment ofFrontiers in microbiology · 2026
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  6. The cystic fibrosis pathogenJournal of medical microbiology · 2025
    Article
  7. Article
  8. Article
  9. Pathogenesis ofInfection and immunity · 2023
    Article
  10. Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brandon M WillsDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Preeti GaraiDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Molly O RiegertDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Felix T SanchezDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Adam M PickrumDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Dara W FrankDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0003-1853-3377
Kenneth L BrockmanDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0002-0339-7504
Medical College of Wisconsin · USNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clinical epidemiology and genomic comparisons of Ax isolates, yet little is known about disease pathology or the role that specific virulence factors play in tissue invasion or damage. Here, we model an acute Ax lung infection in immunocompetent C57BL/6 mice and immunocompromised CF mice, revealing a link between

Indexed as

Achromobacter denitrificansCystic FibrosisGram-Negative Bacterial InfectionsAnimalsDisease Models, AnimalMiceMice, Inbred C57BLVirulence FactorsVirulence FactorsAchromobacterCFTRhost responsemurine lung infection modeltransposon mutants

Identifiers

PMID37255468
PMCPMC10353400
OpenAlexW4378782858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.