Evidence map›Paper›PMID 37255136›Full record

ArticleArquivos brasileiros de cardiologia2023

Investigation of the Relationship Between Triglycerides-Glucose İndex and Coronary Slow Flow: A Retrospective Case-Control Study.

Mustafa Kaplangoray, Kenan Toprak, Fuat Başanalan, Ali Palice, Cihan Aydın, Aykut Demirkıran, Yusuf Cekici

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mustafa KaplangorayDepartamento de Cardiologia - University of Health Sciences Mehmet Akif İnan Research and Training Hospital , Sanlıurfa - Turquia.ORCID 0000-0002-4297-1820
Kenan ToprakRepublic of Turkey Ministry of Health Siverek State Hospital Cardiology Department , Sanlıurfa - Turquia.ORCID 0000-0001-8923-8709
Fuat BaşanalanDepartamento de Cardiologia - University of Health Sciences Mehmet Akif İnan Research and Training Hospital , Sanlıurfa - Turquia.ORCID 0000-0001-8358-722X
Ali PaliceDepartamento de Cardiologia - University of Health Sciences Mehmet Akif İnan Research and Training Hospital , Sanlıurfa - Turquia.ORCID 0000-0001-6560-8031
Cihan AydınDepartamento de Cardiologia , Tekirdag Namık Kemal University , Tekirdağ - Turquia.ORCID 0000-0002-1401-5727
Aykut DemirkıranDepartamento de Cardiologia , Tekirdag Namık Kemal University , Tekirdağ - Turquia.ORCID 0000-0001-8322-3514
Yusuf CekiciDepartamento de Cardiologia , University of Health Sciences Adana Health Practice and Research Center , Adana - Turquia.ORCID 0000-0002-4585-3707
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi · TRTekirdağ Namık Kemal University · TRAdana Science and Technology University · TRSivas State Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary slow flow (CSF) refers to delayed distal vessel opacification in the absence of epicardial coronary artery stenosis. The etiopathogenic mechanism of CSF is still unclear.

objectivesThis study investigates the relationship between CSF and the triglyceride-glucose (TyG) index.

methodsThe study sample consisted of 118 CSF patients and 105 patients with normal coronary flow (NCF). The coronary flow rate was measured via the Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) method in all patients. The TyG index was calculated as the logarithm of the [fasting triglyceride (mg/dL)×fasting glucose (mg/dL)]/2 value. A significance level of < 0.05 was adopted as statistically significant.

resultsThe TyG index, low-density lipoprotein (LDL), body mass index (BMI), neutrophil-to-lymphocyte ratio (NLR) and TFC values, male ratio, and the ratio of smokers were higher, whereas high-density lipoprotein (HDL) levels were significantly lower in the CSF group compared to the NCF group (p<0,05). The correlation analysis revealed that CSF was significantly correlated with TyG index, BMI, NLR, and HDL values. The strongest of these correlations was between CSF and TyG index (r= 0.57, p<0.001). Additionally, the multivariate analysis revealed that TyG index, BMI, NLR ratio, and male gender were independent predictors for CSF (p<0.05). Receiver operating characteristic (ROC) curve analysis indicated that a cut-off value of ≥ 9.28 for the TyG index predicted CSF with a sensitivity of 78% and a specificity of 78.1% [Area under the curve (AUC): 0.868 and 95% Confidence Interval (CI): 0.823-0.914].

conclusionThe findings of this study revealed a very strong relationship between CSF and TyG index.

Indexed as

Blood GlucoseGlucoseBiomarkersCase-Control StudiesHumansMaleRetrospective StudiesTriglyceridesBiomarkersBlood GlucoseGlucoseTriglycerides

Identifiers

PMID37255136
PMCPMC10389274
OpenAlexW4377041640

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.