Evidence map›Paper›PMID 37253969›Full record

ArticleScientific reports2023

The prevalence and burden of Rome IV bowel disorders of gut brain interaction in patients with non-alcoholic fatty liver disease: a cross-sectional study.

Huw Purssell, Lucy Bennett, Oliver Street, Karen Piper Hanley, Neil Hanley, Dipesh H Vasant, Varinder S Athwal

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huw PurssellDepartment of Gastroenterology and Hepatology, Manchester University NHS Foundation Trust, Manchester, UK.
Lucy BennettNIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
Oliver StreetDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Karen Piper HanleyDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Neil HanleyDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0003-3234-4038
Dipesh H VasantDepartment of Gastroenterology and Hepatology, Manchester University NHS Foundation Trust, Manchester, UK.
Varinder S AthwalDepartment of Gastroenterology and Hepatology, Manchester University NHS Foundation Trust, Manchester, UK. Varinder.Athwal@manchester.ac.uk.ORCID 0000-0002-1684-721X

Funding

Department of Health BRC-1215-20003Medical Research Council MR/P023541/1Wellcome Trust 203128/Z/16/Z
6 · The paper itself

Abstract

Rome IV bowel disorders of gut brain interaction (DGBI) and non-alcoholic fatty liver disease (NAFLD) are highly prevalent entities with overlapping pathophysiology and risk factors. We aimed to evaluate the prevalence and burden of Rome IV irritable bowel syndrome (IBS) in patients with NAFLD. Patients diagnosed with NAFLD were recruited from a specialist liver clinic. All participants completed assessments to determine liver fibrosis severity, including liver stiffness measurement (LSM), completed the Rome IV diagnostic questionnaire for bowel disorders of gut brain interaction, the IBS symptom severity score (IBS-SSS), and the EQ-5D-5L to measure of quality-of-life (QoL). 142 patients with NAFLD (71 (50%) female, mean age 53.5 (SD ± 14.9), BMI 35.2 (SD ± 8.1) kg/M

Indexed as

Brain DiseasesIrritable Bowel SyndromeNon-alcoholic Fatty Liver DiseaseActivities of Daily LivingBrainCross-Sectional StudiesFemaleHumansLiver CirrhosisMaleMiddle AgedPrevalenceQuality of LifeRomeSurveys and Questionnaires

Identifiers

PMID37253969
PMCPMC10229668

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.