Evidence map›Paper›PMID 37253616›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2023

Nitrous oxide-induced myeloneuropathy: a case series.

Devan Mair, Alvar Paris, Safiya A Zaloum, Laura M White, Katherine C Dodd, Christina Englezou, Farhin Patel, Siraj Abualnaja, James B Lilleker, David Gosal and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The boon and bane of nitrous oxide.European archives of psychiatry and clinical neuroscience · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Observational
  19. [Nitrous oxide as a party drug].Die Anaesthesiologie · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Devan MairQueen Mary University of London Barts and The London School of Medicine and Dentistry, London, UK.ORCID 0000-0002-9461-7014
Alvar ParisBarts Health NHS Trust, London, UK.
Safiya A ZaloumQueen Mary University of London Barts and The London School of Medicine and Dentistry, London, UK.
Laura M WhiteManchester Centre for Clinical Neuroscience, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Katherine C DoddManchester Centre for Clinical Neuroscience, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Christina EnglezouDepartment of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Farhin PatelQueen Mary University of London Barts and The London School of Medicine and Dentistry, London, UK.
Siraj AbualnajaQueen Mary University of London Barts and The London School of Medicine and Dentistry, London, UK.
James B LillekerManchester Centre for Clinical Neuroscience, Northern Care Alliance NHS Foundation Trust, Salford, UK.
David GosalManchester Centre for Clinical Neuroscience, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Tom HaytonDepartment of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Di LiangDepartment of Neurosciences, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Holger AllroggenDepartment of Neurosciences, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Mark PucciUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Stephen KeddieBarts Health NHS Trust, London, UK.ORCID 0000-0002-2102-6053
Alastair J NoyceBarts Health NHS Trust, London, UK a.noyce@qmul.ac.uk.
Queen Mary University of London · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBUniversity of Manchester · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNitrous oxide (N

methodsWe describe 119 patients with N

resultsParaesthesia was the presenting complaint in 85% of cases, with the lower limbs more commonly affected than the upper limbs. Gait ataxia was common, and bladder and bowel disturbance were frequent additional symptoms. The mid-cervical region of the spinal cord (C3-C5) was most often affected on MRI T2-weighted imaging. The number of N

conclusionsPreventable neurological harm from N

Indexed as

Spinal Cord DiseasesSubstance-Related DisordersHumansNitrous OxideParesthesiaNitrous OxideB12 deficiencyclinical neurologymyelopathyneuropathy

Identifiers

PMID37253616
PMCPMC10447413
OpenAlexW4378782143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.