ArticleInternational journal of epidemiology2023
Ionizing radiation and solid cancer mortality among US nuclear facility workers.
Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Transcriptomic analysis of lncRNA-miRNA-mRNA competing endogenous RNA regulatory networks in radiation-induced mouse thymic degeneration.Immunologic research · 2026Article
- Occupational radiation exposure and cause-specific mortality in a cohort of Canadian medical workers.International archives of occupational and environmental health · 2026Article
- Cancer Mortality after Protracted Low-level Radiation Exposure for Early and Contemporary Workers in Two Large Occupational Cohorts in the U.S. Million Person Study.Radiation research · 2025Article
- Protracted exposure to low-dose ionising radiation and cancer incidence among Canadian nuclear power plant workers.Occupational and environmental medicine · 2025Article
- Confounding Effects of Lifestyle Factors in Cancer Risk Estimation for Occupational Radiation Exposure.Safety and health at work · 2025Article
- Worker studies and their interpretation.Journal of radiological protection : official journal of the Society for Radiological Protection · 2025Article
- Analysis of the association between long-term exposure to low-dose ionizing radiation and dyslipidemia and its components in medical radiologists: The mediating role of inflammatory markers.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Site-specific cancer mortality after low-level exposure to ionizing radiation: findings from an update of the International Nuclear Workers Study (INWORKS).American journal of epidemiology · 2025Article
- Low-dose ionizing radiation and the exposure-lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers.Frontiers in public health · 2025Article
- The impact of low-dose gamma radiation on immune modulation in a mouse model of spontaneous mammary gland tumorigenesis.Frontiers in immunology · 2025Article
- Causes of death and trends in mortality from the year 2000 to 2017 in patients with acute myocardial infarction.Annals of medicine · 2024Article
- Updated findings on temporal variation in radiation-effects on cancer mortality in an international cohort of nuclear workers (INWORKS).European journal of epidemiology · 2024Article
- Leukaemia, lymphoma, and multiple myeloma mortality after low-level exposure to ionising radiation in nuclear workers (INWORKS): updated findings from an international cohort study.The Lancet. Haematology · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Incidence risk of hepatobiliary malignant neoplasms in the cohort of workers chronically exposed to ionizing radiation.Scientific reports · 2024Article
- Advances in TEE-Centric Intraprocedural Multimodal Image Guidance for Congenital and Structural Heart Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Cancer mortality after low dose exposure to ionising radiation in workers in France, the United Kingdom, and the United States (INWORKS): cohort study.BMJ (Clinical research ed.) · 2023Article
- Inverse dose protraction effects of low-LET radiation: Evidence and significance.Mutation research. Reviews in mutation researchReview
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
backgroundThe risk of solid cancers from low-level protracted ionizing radiation is not well characterized. Nuclear workers provide valuable information on the effects of ionizing radiation in contemporary exposure scenarios relevant to workers and the public.
methodsWe evaluated the association between penetrating ionizing radiation exposure and solid cancer mortality among a pooled cohort of nuclear workers in the USA, with extended follow-up to examine cancers with long latencies. This analysis includes 101 363 workers from five nuclear facilities, with 12 069 solid cancer deaths between 1944 and 2016. The association between cumulative equivalent dose measured in sieverts (Sv) and solid cancer subtypes were modelled as the excess relative rate per Sv (ERR Sv-1) using Cox regression.
resultsFor the association between ionizing radiation exposure and all solid cancer mortality we observed an elevated rate (ERR Sv-1=0.19; 95% CI: -0.10, 0.52), which was higher among a contemporary sub-cohort of workers first hired in 1960 or later (ERR Sv-1= 2.23; 95% CI: 1.13, 3.49). Similarly, we observed an elevated rate for lung cancer mortality (ERR Sv-1= 0.65; 95% CI: 0.09, 1.30) that was higher among contemporary hires (ERR Sv-1= 2.90; 95% CI: 1.00, 5.26).
conclusionsAlthough concerns remain about confounding, measurement error and precision, this analysis strengthens the evidence base indicating there are radiogenic risks for several solid cancer types.
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