Evidence map›Paper›PMID 37252353›Full record

ArticleACS central science2023

Design of Soft Material Surfaces with Rationally Tuned Water Diffusivity.

Audra J DeStefano, My Nguyen, Glenn H Fredrickson, Songi Han, Rachel A Segalman

Abstract read
In one paragraph

Article in ACS central science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Audra J DeStefanoDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID https://orcid.org/0000-0003-1047-2637
My NguyenDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID https://orcid.org/0000-0002-5567-9378
Glenn H FredricksonDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID https://orcid.org/0000-0002-6716-9017
Songi HanDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID https://orcid.org/0000-0001-6489-6246
Rachel A SegalmanDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.ORCID https://orcid.org/0000-0002-4292-5103

Funding

Water as essential building blocks to direct protein structure and functionR35GM136411 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Songi Han · 2020 to 2026
$2.4M
NIGMS NIH HHS R35 GM136411
6 · The paper itself

Abstract

Water structure and dynamics can be key modulators of adsorption, separations, and reactions at soft material interfaces, but systematically tuning water environments in an aqueous, accessible, and functionalizable material platform has been elusive. This work leverages variations in excluded volume to control and measure water diffusivity as a function of position within polymeric micelles using Overhauser dynamic nuclear polarization spectroscopy. Specifically, a versatile materials platform consisting of sequence-defined polypeptoids simultaneously offers a route to controlling the functional group position and a unique opportunity to generate a water diffusivity gradient extending away from the polymer micelle core. These results demonstrate an avenue not only to rationally design the chemical and structural properties of polymer surfaces but also to design and tune the local water dynamics that, in turn, can adjust the local activity for solutes.

Identifiers

PMID37252353
PMCPMC10214527

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.