ReviewCurrent pediatrics reports2023
Pediatric Sepsis: a Summary of Current Definitions and Management Recommendations.
Review in Current pediatrics reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 45 citations in OpenAlex.
- Fluid accumulation and outcomes in children receiving continuous kidney replacement therapy: an appraisal of the WE-ROCK registry.Pediatric nephrology (Berlin, Germany) · 2026Article
- Epidemiology, multimorbidity patterns and outcomes of paediatric sepsis admissions in Ireland 2020-2025.European journal of pediatrics · 2026Observational
- Evaluation of Sepsis Algorithmic Alerts Among Hospitalized Pediatric Patients in Qatar: A Retrospective Cohort Study.Health science reports · 2026Article
- Hypophosphatemia in Pediatric Patients on Continuous Kidney Replacement Therapy-A WE-ROCK Study.Research square · 2026Article
- Serial assessment of pentraxin-3 and presepsin in pediatric sepsis: a prospective study.European journal of pediatrics · 2026Article
- Proteomic biomarkers for early diagnosis and prognosis in pediatric sepsis.World journal of clinical pediatrics · 2026Article
- Anti-Inflammatory and Protective Role of tiRNA-Glu-TTC-003 in Pediatric Sepsis Via TREM2/TLR4 Signaling Modulation.Inflammation · 2026Article
- Implementation of central venous access device care bundles using a plan-do-study-act approach to reduce central line-associated bloodstream infection in children at a tertiary hospital in Indonesia.Frontiers in pediatrics · 2026Article
- Article
- Risk Factors for Sepsis in Pediatric All During Induction Chemotherapy-Induced Neutropenia: A Single-Center Retrospective Study.Infection and drug resistance · 2026Article
- Clinical Scores for Predicting Outcomes in Pediatric Oncology Sepsis: A Systematic Review and Meta-Analysis.Critical care research and practice · 2026Review
- Metabolomics analysis identifies differential metabolites and potential diagnostic biomarkers among pediatric sepsis subtypes.PloS one · 2026Article
- Metabolomics of Sepsis and Acute Kidney Injury in Infants and Children: Current Challenges in Prevention, Diagnosis, and Management.Infectious diseases and therapy · 2025Review
- Training for Pediatric Sepsis-A Medical Education Perspective and Potential Role of Artificial Intelligence.Children (Basel, Switzerland) · 2025Review
- Pediatric sepsis prediction: Human in the loop framework.PLOS digital health · 2025Article
- Comparison of venous lactate values on blood gas analyser versus laboratory autoanalyser: A preliminary study.The Indian journal of medical research · 2025Article
- Post-COVID-19-pandemic changes and clinical characteristics of invasive group a streptococcal infections from 2015 to 2023.Infection · 2025Article
- Procalcitonin and C-reactive protein as early diagnostic markers of sepsis or septic shock in children who presented with fever to the pediatric emergency department at a tertiary hospital, in Riyadh, Saudi Arabia.International journal of emergency medicine · 2025Article
- Article
- Construction and efficacy evaluation of a model for early diagnosis of pediatric sepsis based on LASSO-logistic regression.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose of Review: Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement. Recent Findings: Controversy remains regarding the accurate definition, resuscitation fluid volume and type, choice of vasoactive/inotropic agents, and antibiotic depending upon specific infection risks. Many adjunctive therapies have been suggested with theoretical benefits, although definitive recommendations are not yet supported by data. We describe best practice recommendations based on international guidelines, a review of primary literature, and a discussion of ongoing clinical trials and the nuances of therapeutic choices. Summary: Early diagnosis and timely intervention with antibiotics, fluid resuscitation, and vasoactive medications are the most important interventions in sepsis. The implementation of protocols, resource-adjusted sepsis bundles, and advanced technologies will have an impact on reducing sepsis mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.