ArticleSaudi journal of biological sciences2023
Effects of exposure to imidacloprid contaminated feed on the visceral organs of adult male rabbits (
Article in Saudi journal of biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Comparative habitat-associated patterns of pathomorphological changes in the internal organs of the European brown hare (Veterinary world · 2026Article
- Combination of Luteolin and Silibinin Has Hepatoprotective Effects on Rats' Liver Fibrosis Induced by Thioacetamide.Current drug delivery · 2025Article
- Dietary Curcumin Modulating Effect on Performance, Antioxidant Status, and Immune-Related Response of Broiler Chickens Exposed to Imidacloprid Insecticide.Animals : an open access journal from MDPI · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The best-known and often used systemic, broad-spectrum neonicotinoid pesticide is imidacloprid (IMI). This study was carried out on adult male rabbits (n = 12) to assess the residual effects of exposure to IMI-contaminated diet on the liver, lung, heart, and kidney. Pesticide-exposed rabbits (n = 6) received IMI contaminated green grass (Bildor® 0.5 ml (100 mg)/L water) every alternative day once daily for up to 15 days. The remaining rabbits were fed a standard diet free of pesticides as a control. During routine monitoring of the rabbits throughout the experiment, there were no apparent toxic symptoms identified. On days 16, after deep anesthesia blood and visceral organs were collected. The levels of hepatic serum aspartate transaminase and alanine transaminase were considerably elevated in IMI-exposed rabbits (p ≤ 0.05). Thin layer chromatography revealed that the residue of IMI was at the detectable level in the liver and stomach. Histopathologically, the liver revealed coagulation necrosis with granulomatous inflammation and congestion in portal areas with dilated and congested central veins. The lungs showed congestion of blood vessels and granulomatous inflammation around the terminal bronchiole. Accumulations of inflammatory cells were observed in the cortico-medullary junction in the kidney. The heart showed necrosis and infiltration of mononuclear cells within the cardiac muscles. The findings of the current study emphasize that IMI-contaminated feed exposure causes toxicity into the cellular level of different visceral organs of adult male rabbits and it may also cause the similar toxic effects of the other mammals specially the occupationally exposed persons.
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