Evidence map›Paper›PMID 37252208›Full record

ArticleVeterinary and animal science2023

Plasma fatty acid profile in Italian Holstein-Friesian dairy cows supplemented with natural polyphenols from the olive plant

Maria Chiara Di Meo, Angela Salzano, Tiziana Zotti, Antonio Palladino, Daniela Giaquinto, Lucianna Maruccio, Riccardo Romanucci, Mariapina Rocco, Armando Zarrelli, Michael J D'Occhio and 2 more

Abstract read
In one paragraph

Article in Veterinary and animal science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. An Integrated Approach to Evaluate the Influence of DietaryAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. A Diet Supplemented with Oil-Free Olive Pulp Flour (MOP-ManniOlivePowderAnimals : an open access journal from MDPI · 2024
    Article
  4. Article
  5. Effects ofAnimals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maria Chiara Di MeoDepartment of Sciences and Technologies (DST), University of Sannio, Benevento, BN 82100, Italy.
Angela SalzanoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, NA 80137, Italy.
Tiziana ZottiDepartment of Sciences and Technologies (DST), University of Sannio, Benevento, BN 82100, Italy.
Antonio PalladinoDepartment of Agricultural Science, University of Naples Federico II, Portici, NA 80055, Italy.
Daniela GiaquintoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, NA 80137, Italy.
Lucianna MaruccioDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, NA 80137, Italy.
Riccardo RomanucciDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, NA 80137, Italy.
Mariapina RoccoDepartment of Sciences and Technologies (DST), University of Sannio, Benevento, BN 82100, Italy.
Armando ZarrelliDepartment of Chemical Sciences, University of Naples Federico II, Naples, NA 80126, Italy.
Michael J D'OcchioSchool of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW 2000, Australia.
Giuseppe CampanileDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, NA 80137, Italy.
Ettore VarricchioDepartment of Sciences and Technologies (DST), University of Sannio, Benevento, BN 82100, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of supplementing with natural functional feed on the plasma fatty acid profile of lactating Italian Holstein-Friesian dairy cows. Thirty cows in mid-lactation received the natural olive extract PHENOFEED DRY (500 mg/cow/day) which mainly comprises hydroxytyrosol, tyrosol and verbascoside. The total content of polyphenols and the antioxidant power of standard feed, enriched feed and pure extract was evaluated respectively by Folin-Ciocalteu and DPPH assay, and a characterization in HPLC-UV (High-Performance Liquid Chromatography-Ultraviolet) of bioactive molecules present in the extract PHENOFEED DRY was performed. PHENOFEED DRY was provided for 60 days, and the plasma profile of fatty acids was determined by Gas Chromatography. The administration of enriched feed resulted in an increase in the ratio of Omega-6 to Omega-3 polyunsaturated fatty acids from 3:1 to 4:1 (p<0.001). This was not influenced by the calving order. The addition of polyphenols helped to keep monounsaturated (MUFA) and saturated (SFA) levels constant and results in a significant increase in polyunsaturated (PUFA) fatty acid after 15 days of administration. The Omega-6/Omega-3 ratio was in the optimal range. The findings show that inclusion of natural functional food such as plant polyphenols helps to maintain a healthy blood fatty acid profile in lactating dairy cows.

Indexed as

Antioxidant activityDairy cowsFatty acidsFunctional feedHolsteinOlea Europaea L. polyphenols

Identifiers

PMID37252208
PMCPMC10220399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.