ReviewFrontiers in cardiovascular medicine2023
Incidence and risk factors of deep vein thrombosis in patients with spinal cord injury: a systematic review with meta-analysis.
Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Feasibility and safety of two weeks of blood flow restriction exercise in individuals with spinal cord injury.The journal of spinal cord medicine · 2026Trial
- Analysis of risk factors associated with pulmonary embolism in patients with spinal cord injury: A meta-analysis.Clinics (Sao Paulo, Brazil) · 2026Review
- Perioperative inflammatory and coagulation biomarkers for predicting venous thromboembolism after lower limb fracture surgery.Thrombosis journal · 2026Article
- Graduated Compression Stockings for Thromboprophylaxis in Orthopaedic and Trauma Surgery: A Rapid Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Latent profile analysis and influencing factors of post-traumatic stress disorder symptoms in young and middle-aged spinal cord injury patients.BMC psychiatry · 2025Article
- Traumatic vs. Non-Traumatic Spinal Cord Injury-Epidemiology, Complications, and Neurological Status During Rehabilitation.Journal of clinical medicine · 2025Article
- Multifaceted challenges of deep venous thrombosis in the setting tetraplegia and ulcerative colitis: case report.Spinal cord series and cases · 2025Article
- Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury.Journal of translational medicine · 2025Article
- The optimal dosage of aspirin for preventing preeclampsia in high-risk pregnant women: A network meta-analysis of 23 randomized controlled trials.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS).World journal of emergency surgery : WJES · 2024Article
- Relationship Between the Systemic Immune-Inflammation Index and Deep Venous Thrombosis After Spinal Cord Injury: A Cross-Sectional Study.Journal of inflammation research · 2024Article
- Risk factors for postoperative DVT exacerbation or new DVT in patients with spinal cord injury complicated with cervical fracture.Frontiers in cardiovascular medicine · 2024Article
- Article
- Analysis of Risk Factors for Postoperative Deep Vein Thrombosis in Traumatic Spinal Fracture Complicated with Spinal Cord Injury.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Spinal cord injury (SCI) is a highly disabling disease with huge public health burden. The complications associated with it, especially deep vein thrombosis (DVT), further aggravate the disability. Objective: To explore the incidence and risk factors of DVT after SCI, in order to provide guidance for disease prevention in the future. Methods: A search was performed on PubMed, Web of Science, Embase, and Cochrane database up to November 9, 2022. Literature screening, information extraction and quality evaluation were performed by two researchers. The data was later combined by metaprop and metan commands in STATA 16.0. Results: A total of 101 articles were included, including 223,221 patients. Meta-analysis showed that the overall incidence of DVT was 9.3% (95% CI: 8.2%-10.6%), and the incidence of DVT in patients with acute and chronic SCI was 10.9% (95% CI: 8.7%-13.2%) and 5.3% (95% CI: 2.2%-9.7%), respectively. The incidence of DVT decreased gradually with the accumulation of publication years and sample size. However, the annual incidence of DVT has increased since 2017. There are 24 kinds of risk factors that may contribute to the formation of DVT, involving multiple aspects of the baseline characteristics of the patient, biochemical indicators, severity of SCI, and comorbidities. Conclusions: The incidence of DVT after SCI is high and has been gradually increasing in recent years. Moreover, there are numerous risk factors associated with DVT. Comprehensive preventive measures need to be taken as early as possible in the future. Systematic Review Registration: www.crd.york.ac.uk/prospero, identifier CRD42022377466.
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