Evidence map›Paper›PMID 37252117›Full record

ArticleFrontiers in cardiovascular medicine2023

Evaluating heart rate variability with 10 second multichannel electrocardiograms in a large population-based sample.

Elischa Krause, Marcus Vollmer, Katharina Wittfeld, Antoine Weihs, Stefan Frenzel, Marcus Dörr, Lars Kaderali, Stephan B Felix, Beate Stubbe, Ralf Ewert and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Distinct brain systems support afferent and efferent autonomic activity.Social cognitive and affective neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Elischa KrauseDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Marcus VollmerInstitute of Bioinformatics, University Medicine Greifswald, Greifswald, Germany.
Katharina WittfeldDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Antoine WeihsDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Stefan FrenzelDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Marcus DörrGerman Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, Greifswald, Germany.
Lars KaderaliInstitute of Bioinformatics, University Medicine Greifswald, Greifswald, Germany.
Stephan B FelixGerman Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, Greifswald, Germany.
Beate StubbeDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Ralf EwertDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Henry VölzkeDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Hans J GrabeDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEGerman Center for Neurodegenerative Diseases · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Heart rate variability (HRV), defined as the variability of consecutive heart beats, is an important biomarker for dysregulations of the autonomic nervous system (ANS) and is associated with the development, course, and outcome of a variety of mental and physical health problems. While guidelines recommend using 5 min electrocardiograms (ECG), recent studies showed that 10 s might be sufficient for deriving vagal-mediated HRV. However, the validity and applicability of this approach for risk prediction in epidemiological studies is currently unclear to be used. Methods: This study evaluates vagal-mediated HRV with ultra-short HRV (usHRV) based on 10 s multichannel ECG recordings of Results: High correlations ( Conclusion: This study provides evidence that usHRV derived from 10 s ECG might function as a proxy of vagal-mediated HRV with similar characteristics. This allows the investigation of ANS dysregulation with ECGs that are routinely performed in epidemiological studies to identify protective and risk factors for various mental and physical health problems.

Indexed as

biomarkerdepressionECGheart rate variability (HRV)PHQ-9RMSSD

Identifiers

PMID37252117
PMCPMC10213655
OpenAlexW4376279623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.