Evidence map›Paper›PMID 37252104›Full record

ArticleRSC medicinal chemistry2023

Identification and analysis of small molecule inhibitors of FosB from

Skye Travis, Keith D Green, Nishad Thamban Chandrika, Allan H Pang, Patrick A Frantom, Oleg V Tsodikov, Sylvie Garneau-Tsodikova, Matthew K Thompson

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Skye TravisDepartment of Chemistry & Biochemistry, The University of Alabama Box 870336, 250 Hackberry Lane Tuscaloosa AL 35487 USA mthompson10@ua.edu +(205) 348 8439.ORCID https://orcid.org/0000-0001-9329-6805
Keith D GreenDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky 789 South Limestone St. Lexington KY 40536 USA.
Nishad Thamban ChandrikaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky 789 South Limestone St. Lexington KY 40536 USA.
Allan H PangDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky 789 South Limestone St. Lexington KY 40536 USA.ORCID https://orcid.org/0000-0003-4786-6445
Patrick A FrantomDepartment of Chemistry & Biochemistry, The University of Alabama Box 870336, 250 Hackberry Lane Tuscaloosa AL 35487 USA mthompson10@ua.edu +(205) 348 8439.ORCID https://orcid.org/0000-0001-7655-5967
Oleg V TsodikovDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky 789 South Limestone St. Lexington KY 40536 USA.
Sylvie Garneau-TsodikovaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky 789 South Limestone St. Lexington KY 40536 USA.ORCID https://orcid.org/0000-0002-7961-5555
Matthew K ThompsonDepartment of Chemistry & Biochemistry, The University of Alabama Box 870336, 250 Hackberry Lane Tuscaloosa AL 35487 USA mthompson10@ua.edu +(205) 348 8439.ORCID https://orcid.org/0000-0002-1964-3896
University of Kentucky · USUniversity of Alabama · US

Funding

Bruker AVANCE NEO 600 MHz High-Performance Digital NMR SpectrometerS10OD028690 · OD · UNIVERSITY OF KENTUCKY · PI GARNEAU-TSODIKOVA, SYLVIE · 2020 to 2020
$1.4M
Combating Fosfomycin Resistance in Methicillin-Resistant Staphylococcus aureusR15GM148956 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI THOMPSON, MATTHEW KYLE · 2022 to 2022
$430k
NIGMS NIH HHS R15 GM148956NIH HHS S10 OD028690
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) poses a significant threat to human health around the world. Though bacterial pathogens can develop resistance through a variety of mechanisms, one of the most prevalent is the production of antibiotic-modifying enzymes like FosB, a Mn

Identifiers

PMID37252104
PMCPMC10211316
OpenAlexW4367011930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.